The Research Work Acts
The Research Work Acts (HR3699) was introduced in the United States House of Representatives last month. The purpose of the bill is to appeal the NIH Open Access Mandate that, (as you all know by now), requires authors to deposit their final manuscript of peer-reviewed papers into pubmed central if they arise from NIH funding. The bill is supported by the Association of American Publishers and the Copyright Alliance. Open access publishers, like Biomed Central, oppose the bill, as do Nature Publishing Group, the American Association of Science, university presses, such as MIT Press, Rockefeller University Press, and library groups such as the American Library Association and the Medical Library Association.
This NIH Open Access Mandate has allowed the public (including the Fox Chase community) to access significant papers in science and medicine without the barrier of a subscription to the journal that the paper appears.
Top Articles in December from F1000 – Have you read these yet?
Two ‘exceptional’ ratings for this demonstration that pathways involved in Alzheimer’s disease are conserved in yeast, and suggesting that intracellular membrane trafficking mechanisms may be targets to protect against neurodegeneration.
Treusch et al. Science. 2011 Dec 2; 334:1241-5http://www.sciencemag.org/content/334/6060/1241
Details the complex inter-relationship between nutrient absorption and the host defense in the gut, and may provide insight into why malnourishment persists in developing countries when nutritious food is available.
Shulzhenko et al. Nat Med. 2011; 17:1585-93http://www.nature.com/nm/journal/v17/n12/full/nm.2505.html
Adenovirus-associated virus vector-mediated gene transfer in hemophilia B.
A new report, classified by two evaluators as a ‘technical advance’, on a significant step forward in AVV-mediated human gene therapy, with encouraging results in hemophilia B patients.
Nathwani et al. N Engl J Med. 2011 Dec 22; 365:2357-65http://www.nejm.org/doi/full/10.1056/NEJMoa1108046
Frequent pathway mutations of splicing machinery in myelodysplasia.
The discovery of frequent acquired mutations of RNA splicing machinery sheds light on the puzzling pathogenesis of MDS and opens up new areas for research and therapy.
Yoshida et al. Nature. 2011 Oct 6; 478:64-9http://www.nature.com/nature/journal/v478/n7367/full/nature10496.html
Suggests the intriguing possibility that other important mechanisms for regulating recombination remain to be elucidated.
Muoz-Fuentes et al. PLoS One. 2011; 6: e25498http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0025498
Emergence of Klebsiella pneumoniae isolate co-producing NDM-1 with KPC-2 from India.
Identification of a highly-resistant pathogen that produces two mobile antibiotic-resistant enzymes which were formerly only identified individually; a warning that pathogens expressing both carbapenemases will be susceptible to few, if any, antibacterial agents.
Kumarasamy et al. J Antimicrob Chemother. 2012 Jan; 67:243-4http://jac.oxfordjournals.org/content/67/1/243
Please note: We no longer have an institutional subscription to F1000; if you miss it please let Beth know. I have started to see F100 icons in PubMed for articles reviewed in F1000
Science Breakthrough of the Year 2011
Science’s editors and news staff have selected the finding that antiretroviral drugs reduce the risk of heterosexual transmission of HIV as its Breakthrough of the Year 2011. Read it here: http://www.sciencemag.org/content/334/6063/1628.full
Read Science’s Areas to Watch in 2012 here: http://www.sciencemag.org/content/334/6063/1630.full
More Reading from the BMJ
Did you catch the BMJ’s annual Christmas issue? Here’s the link for the issue : http://www.bmj.com/content/343/7837. It’s packed with interesting-sounding articles like:
“What Three Wise Men have to say about diagnosis”
“Is 27 really a dangerous age for famous musicians?
“Beethoven’s deafness and his three styles”
Conference lists
Planning to attend a conference this year? Here are lists that may help you choose one.
Oncology Meetings from Oncology Times
http://journals.lww.com/oncology-times/Pages/conferences.aspx
Upcoming Medical Meetings from New England Journal of Medicine
http://www.nejm.org/medical-conference
HON (Health on the Net) Worldwide medical meetings
http://www.hon.ch/cgi-bin/confevent
JAMA Calendar of Events
http://pubs.ama-assn.org/cgi/calendarcontent
The NEJM is celebrating a big birthday…200 years in 2012!
Throughout 2012 the NEJM will mark this anniversary with special content and features on its anniversary website : nejm200.nejm.org
Take the Historical Image Challenge, vote for the most important article, enjoy the interactive historical timeline, read weekly special articles, and read and post what colleagues have to say.
What’s Happening in the Library
New LibGuide!
Alex has prepared a new libguide on Current Awareness Alerting; check it out here http://libguides.fccc.edu/alerts
Contact us and we can help you keep up with literature that you don’t want to miss!
New Version of EndNote!
EndNot X5 is here! You can go to the EndNote libguide http://libguides.fccc.edu/endnote for instructions and downloading info. Look for announcements of Endnote classes that Alex has begun teaching.
New Tool – My Bibliography
Would you like a free and easy tool that you can use to create and maintain your bibliography? Worry no more – it’s available withPubMed’s MyNCBI! It also allows you to check NIH Compliance by syncing with your ERA Commons Account and allows delegates (like your secretary and/or librarian) to setup and maintain your bibliography. Contact Beth for more info and a demo.
Coming soon – Earn and redeem CME credit automatically when you research topics using UpToDate!
The IT folks and I are working to integrate UpToDate with our clinical system so that when clinicians access UpTo Date from the launchpad they will automatically earn and accrue CME credit when searching topics in UpToDate. A simple registration is necessary to redeem the credits and print out a certificate. Look for more info coming soon.
