Staff Publications Received in July 2014

Staff Publications Received in July 2014

  1. Boyd J. Genetic predisposition to breast cancer: the next chapters. Cancer. 2014;120(7):932-4. Read the article.

2.         Brusilovsky M, Radinsky O, Yossef R, Campbell KS, Porgador A. Carbohydrate-mediated modulation of NK cell receptor function: structural and functional influences of heparan sulfate moieties expressed on NK cell surface. Frontiers in oncology. 2014;4:185. PMCID: Pmc4100077. Read the article.

  1. Burger RA, Brady MF, Bookman MA, Monk BJ, Walker JL, Homesley HD, Fowler J, Greer BE, Boente M, Fleming GF, Lim PC, Rubin SC, Katsumata N, Liang SX. Risk factors for GI adverse events in a phase III randomized trial of bevacizumab in first-line therapy of advanced ovarian cancer: A Gynecologic Oncology Group Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2014;32(12):1210-7. PMCID: Pmc3986384. Read the article.
  1. Cohen SJ, Konski AA, Putnam S, Ball DS, Meyer JE, Yu JQ, Astsaturov I, Marlow C, Dickens A, Cade DN, Meropol NJ. Phase I study of capecitabine combined with radioembolization using yttrium-90 resin microspheres (SIR-Spheres) in patients with advanced cancer. British journal of cancer. 2014;111(2):265-71. PMCID: Pmc4102951. Read the article.
  1. Cole M, Parajuli S, Laske D, Goldstein L, Morrison T, Mukherjee A, Tumelty K, Tetzlaff E, von Mehren M, Inniss S. Peripheral primitive neuroectodermal tumor of the dura in a 51-year-old woman following intensive treatment for breast cancer. The American journal of case reports. 2014;15:294-9. PMCID: Pmc4102603. Read the article.
  1. Doss M. CT Radiation Dose Optimization Is Not Advisable in View of Current Knowledge. Journal of the American College of Radiology : JACR. 2014;11(7):745-6. Read the article.
  1. Doss M, Egleston BL, Litwin S. Atomic Bomb Survivor Cataract Surgery Prevalence Data are Consistent with Non-zero Threshold Dose-Comment on Article by Nakashima et al. 2013. Health physics. 2014;107(3):262-3. PMCID: Pmc4123214. [Comment]. Read the article.
  1. Doss M, Little MP, Orton CG. Point/Counterpoint: Low-dose radiation is beneficial, not harmful. Medical physics. 2014;41(7):070601. Read the article.

9.  Ettinger DS, Handorf CR, Agulnik M, Bowles DW, Cates JM, Cristea M, Dotan E, Eaton KD, Fidias PM, Gierada D, Gilcrease GW, Godby K, Iyer R, Lenzi R, Phay J, Rashid A, Saltz L, Schwab RB, Shulman LN, Smerage JB, Stevenson MM, Varadhachary GR, Zager JS, Zhen WK, Bergman MA, Freedman-Cass DA. Occult primary, version 3.2014. Journal of the National Comprehensive Cancer Network : JNCCN. 2014;12(7):969-74. Read the article.

10. Fang CY, Ross EA, Pathak HB, Godwin AK, Tseng M. Acculturative Stress and Inflammation Among Chinese Immigrant Women. Psychosomatic Medicine. 2014;76(5):320-6. Read the article.

11. Fleisher L, Ruggieri DG, Miller SM, Manne S, Albrecht T, Buzaglo J, Collins MA, Katz M, Kinzy TG, Liu T, Manning C, Charap ES, Millard J, Miller DM, Poole D, Raivitch S, Roach N, Ross EA, Meropol NJ. Application of best practice approaches for designing decision support tools: The preparatory education about clinical trials (PRE-ACT) study. Patient Education and Counseling. 2014;96(1):63-71. Read the article.

12.       Halliday D, Butler R, Francis D, Thompson J, Joseph M, Ragin CC. Knowledge and Attitudes toward HPV and the HPV Vaccines in The Bahamas. The West Indian medical journal. 2013;62(8):731-7. Read the article.

13. Hensley H, Devarajan K, Johnson JR, Piwnica-Worms D, Godwin AK, von Mehren M, Rink L. Evaluating new therapies in gastrointestinal stromal tumor using in vivo molecular optical imaging. Cancer Biology & Therapy. 2014;15(7):911-8. Read the article.

14.       Herrera AF, Crosby-Thompson A, Friedberg JW, Abel GA, Czuczman MS, Gordon LI, Kaminski MS, Millenson MM, Nademanee AP, Niland JC, Rodig SJ, Rodriguez MA, Zelenetz AD, LaCasce AS. Comparison of Referring and Final Pathology for Patients With T-Cell Lymphoma in the National Comprehensive Cancer Network. Cancer. 2014;120(13):1993-9. Read the article.

15.       Hu W, Kaminski R, Yang F, Zhang Y, Cosentino L, Li F, Luo B, Alvarez-Carbonell D, Garcia-Mesa Y, Karn J, Mo X, Khalili K. RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection. Proceedings of the National Academy of Sciences of the United States of America. 2014;111(31):11461-6. Read the article.

16.       Hurwitz MD, Ghanouni P, Kanaev SV, Iozeffi D, Gianfelice D, Fennessy FM, Kuten A, Meyer JE, LeBlang SD, Roberts A, Choi J, Larner JM, Napoli A, Turkevich VG, Inbar Y, Tempany CM, Pfeffer RM. Magnetic resonance-guided focused ultrasound for patients with painful bone metastases: phase III trial results. Journal of the National Cancer Institute. 2014;106(5). PMCID: Pmc4112926. Read the article.

17. Lodhi N, Kossenkov AV, Tulin AV. Bookmarking promoters in mitotic chromatin: poly(ADP-ribose)polymerase-1 as an epigenetic mark. Nucleic Acids Research. 2014;42(11):7028-38. Read the article.

18. Longacre ML, Ross EA, Fang CY. Caregiving Choice and Emotional Stress Among Cancer Caregivers. Western Journal of Nursing Research. 2014;36(6):806-24. Read the article.

19. Mantia-Smaldone G, Ronner L, Blair A, Gamerman V, Morse C, Orsulic S, Rubin S, Gimotty P, Adams S. The immunomodulatory effects of pegylated liposomal doxorubicin are amplified in BRCA1–deficient ovarian tumors and can be exploited to improve treatment response in a mouse model. Gynecologic oncology. 2014;133(3):584-90. Read the article.

20. Mehra R, Zhu F, Yang DH, Cai KQ, Weaver J, Singh MK, Nikonova AS, Golemis EA, Flieder DB, Cooper HS, Lango M, Ridge JA, Burtness B. Quantification of excision repair cross-complementing group 1 and survival in p16-negative squamous cell head and neck cancers. Clinical cancer research : an official journal of the American Association for Cancer Research. 2013;19(23):6633-43. PMCID: Pmc4045641. Read the article.

21. Meyer JE, Panico VJ, Marconato HM, Sherr DL, Christos P, Pirog EC. HIV positivity but not HPV/p16 status is associated with higher recurrence rate in anal cancer. Journal of gastrointestinal cancer. 2013;44(4):450-5. PMCID: Pmc3963822. Read the article.

22. Min H, Ohira R, Collins MA, Bondy J, Avis NE, Tchuvatkina O, Courtney PK, Moser RP, Shaikh AR, Hesse BW, Cooper M, Reeves D, Lanese B, Helba C, Miller SM, Ross EA. Sharing behavioral data through a grid infrastructure using data standards. Journal of the American Medical Informatics Association. 2014;21(4):642-9. Read the article.

23.       Park DJ, Tao K, Le Calvez-Kelm F, Nguyen-Dumont T, Robinot N, Hammet F, Odefrey F, Tsimiklis H, Teo ZL, Thingholm LB, Young EL, Voegele C, Lonie A, Pope BJ, Roane TC, Bell R, Hu H, Shankaracharya, Huff CD, Ellis J, Li J, Makunin IV, John EM, Andrulis IL, Terry MB, Daly M, Buys SS, Snyder C, Lynch HT, Devilee P, Giles GG, Hopper JL, Feng BJ, Lesueur F, Tavtigian SV, Southey MC, Goldgar DE. Rare Mutations in RINT1 Predispose Carriers to Breast and Lynch Syndrome-Spectrum Cancers. Cancer discovery. 2014;4(7):804-15. Read the article.

24. Patel SA, Sandberg LJ, Ranganath B, Devarajan K, Toto J, Topham NS. Impact of Adjuvant Chemotherapy on Abdominal Wall Hernias and Bulges After Muscle-Sparing Free TRAM Flaps for Breast Reconstruction. Annals of Plastic Surgery. 2014;73(1):62-7. Read the article.

25. Pimtong W, Datta M, Ulrich AM, Rhodes J. Drl.3 governs primitive hematopoiesis in zebrafish. Scientific reports. 2014;4:5791. Read the article.

26. Plimack ER, Hoffman-Censits JH, Viterbo R, Trabulsi EJ, Ross EA, Greenberg RE, Chen DYT, Lallas CD, Wong YN, Lin JQ, Kutikov A, Dotan E, Brennan TA, Palma N, Dulaimi E, Mehrazin R, Boorjian SA, Kelly WK, Uzzo RG, Hudes GR. Accelerated Methotrexate, Vinblastine, Doxorubicin, and Cisplatin Is Safe, Effective, and Efficient Neoadjuvant Treatment for Muscle-Invasive Bladder Cancer: Results of a Multicenter Phase II Study With Molecular Correlates of Response and Toxicity. Journal of Clinical Oncology. 2014;32(18):1895-901. Read the article.

27. Poleshko A, Katz RA. Specifying peripheral heterochromatin during nuclear lamina reassembly. Nucleus-Austin. 2014;5(1):32-9. Read the article.

28. Ragin C, Obikoya-Malomo M, Kim S, Chen ZJ, Flores-Obando R, Gibbs D, Koriyama C, Aguayo F, Koshiol J, Caporaso NE, Carpagnano GE, Ciotti M, Dosaka-Akita H, Fukayama M, Goto A, Spandidos DA, Gorgoulis V, Heideman DAM, van Boerdonk RAA, Hiroshima K, Iwakawa R, Kastrinakis NG, Kinoshita I, Akiba S, Landi MT, Liu HE, Wang JL, Mehra R, Khuri FR, Lim WT, Owonikoko TK, Ramalingam S, Sarchianaki E, Syrjanen K, Tsao MS, Sykes J, Hee SW, Yokota J, Zaravinos A, Taioli E. HPV-associated lung cancers: an international pooled analysis. Carcinogenesis. 2014;35(6):1267-75. Read the article.

29. Seeger-Nukpezah T, Little JL, Serzhanova V, Golemis EA. Cilia and cilia-associated proteins in cancer. Drug discovery today Disease mechanisms. 2013;10(3-4):e135-e42. PMCID: Pmc4073101. Read the article.

30.       Shah NR, Tancioni I, Ward KK, Lawson C, Chen XL, Jean C, Sulzmaier FJ, Uryu S, Miller NLG, Connolly DC, Schlaepfer DD. Analyses of merlin/NF2 connection to FAK inhibitor responsiveness in serous ovarian cancer. Gynecologic oncology. 2014;134(1):104-11. Read the article.

31. Tetzlaff ED, Davey MP. Optimizing adherence to adjuvant imatinib in gastrointestinal stromal tumor. Journal of the advanced practitioner in oncology. 2013;4(4):238-50. PMCID: Pmc4093429. Read the article.

32.       Trotti A, 3rd, Zhang Q, Bentzen SM, Emami B, Hammond ME, Jones CU, Morrison WH, Sagar SM, Ridge JA, Fu KK, Ang KK. Randomized Trial of Hyperfractionation Versus Conventional Fractionation in T2 Squamous Cell Carcinoma of the Vocal Cord (RTOG 9512). International journal of radiation oncology, biology, physics. 2014;89(5):958-63. Read the article.

33.       Tu YF, Hershman DL, Bhalla K, Fiskus W, Pellegrino CM, Andreopoulou E, Makower D, Kalinsky K, Fehn K, Fineberg S, Negassa A, Montgomery LL, Wiechmann LS, Alpaugh RK, Huang M, Sparano JA. A phase I-II study of the histone deacetylase inhibitor vorinostat plus sequential weekly paclitaxel and doxorubicin-cyclophosphamide in locally advanced breast cancer. Breast Cancer Research and Treatment. 2014;146(1):145-52. Read the article.

34.       Wang DS, Patel A, Shukla S, Zhang YK, Wang YJ, Kathawala RJ, Robey RW, Zhang L, Yang DH, Talele TT, Bates SE, Ambudkar SV, Xu RH, Chen ZS. Icotinib antagonizes ABCG2-mediated multidrug resistance, but not the pemetrexed resistance mediated by thymidylate synthase and ABCG2. Oncotarget. 2014;5(12):4529-42. Read the article.

35.       Wu HC, Wang Q, Chung WK, Andrulis IL, Daly MB, John EM, Keegan THM, Knight J, Bradbury AR, Kappil MA, Gurvich I, Santella RM, Terry MB. Correlation of DNA methylation levels in blood and saliva DNA in young girls of the LEGACY Girls study. Epigenetics. 2014;9(7):929-33. Read the article.

36. Zaorsky NG, Doyle LA, Hurwitz MD, Dicker AP, Den RB. Do theoretical potential and advanced technology justify the use of high-dose rate brachytherapy as monotherapy for prostate cancer? Expert Review of Anticancer Therapy. 2014;14(1):39-50. Read the article.

37.       Zelenetz AD, Gordon LI, Wierda WG, Abramson JS, Advani RH, Andreadis CB, Bartlett N, Bellam N, Byrd JC, Czuczman MS, Fayad LE, Fisher RI, Glenn MJ, Harris NL, Hoppe RT, Horwitz SM, Kelsey CR, Kim YH, Krivacic S, LaCasce AS, Nademanee A, Porcu P, Press O, Rabinovitch R, Reddy N, Reid E, Sokol L, Swinnen LJ, Tsien C, Vose JM, Yahalom J, Zafar N, Dwyer M, Sundar H. Non-Hodgkin’s Lymphomas, Version 2.2014. Journal of the National Comprehensive Cancer Network. 2014;12(6):916-45. Read the article.

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Staff Publications Received in June 2014

Staff Publications Received in June 2014

1.         Behrend SW. Survivorship care plans. Oncology nursing forum, 41(4):447-8, 2014. Read the article.

2.         Bichakjian CK, Olencki T, Alam M, Andersen JS, Berg D, Bowen GM, Cheney RT, Daniels GA, Glass LF, Grekin RC, Grossman K, Ho AL, Lewis KD, Lydiatt DD, Morrison WH, Nehal KS, Nelson KC, Nghiem P, Perlis CS, Shaha AR, Thorstad WL, Tuli M, Urist MM, Wang TS, Werchniak AE, Wong SL, Zic JA, McMillian N, Hoffman K, Ho M. Dermatofibrosarcoma protuberans, version 1.2014. Journal of the National Comprehensive Cancer Network : JNCCN, 12(6):863-8, 2014. Read the article.

3.         Bilusic M, Wong YN. Anti-angiogenesis in prostate cancer: knocked down but not out. Asian J Androl, 16(3):372-7, 2014. Read the article.

4.         Burger RA, Brady MF, Bookman MA, Monk BJ, Walker JL, Homesley HD, Fowler J, Greer BE, Boente M, Fleming GF, Lim PC, Rubin SC, Katsumata N, Liang SX. Risk Factors for GI Adverse Events in a Phase III Randomized Trial of Bevacizumab in First-Line Therapy of Advanced Ovarian Cancer: A Gynecologic Oncology Group Study. J Clin Oncol, 32(12):1210-7, 2014. Read the article.

5.         Carlson RW, Larsen JK, McClure J, Fitzgerald L, Venook AP, Benson AB, Anderson BO. International Adaptations of NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Cancer Netw, 12(5):643-8, 2014. Read the article.

6.         Chen DYT, Uzzo RG, Viterbo R. Thinking beyond surgery in the management of renal cell carcinoma: the risk to die from renal cell carcinoma and competing risks of death. World J Urol, 32(3):607-13, 2014. Read the article.

7.         Chiang YT, Ip W, Shao W, Song ZE, Chernoff J, Jin T. Activation of cAMP signaling attenuates impaired hepatic glucose disposal in aged male p21-activated protein kinase-1 knockout mice. Endocrinology, 155(6):2122-32, 2014. Read the article.

8.         Chisari FV, Mason WS, Seeger C. Virology. Comment on “Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA”. Science (New York, NY), 344(6189):1237, 2014. Read the article.

9.         Coit DG, Thompson JA, Andtbacka R, Anker CJ, Bichakjian CK, Carson WE, Daniels GA, Daud A, DiMaio D, Fleming MD, Gonzalez R, Guild V, Halpern AC, Hodi S, Kelley MC, Khushalani NI, Kudchadkar RR, Lange JR, Martini MC, Olszanski AJ, Ross MI, Salama A, Swetter SM, Tanabe KK, Trisal V, Urist MM, McMillian NR, Ho M. Melanoma, Version 4.2014 Featured Updates to the NCCN Guidelines. J Natl Compr Cancer Netw, 12(5):621-9, 2014. Read the article.

10.        Corless CL, Ballman KV, Antonescu CR, Kolesnikova V, Maki RG, Pisters PWT, Blackstein ME, Blanke CD, Demetri GD, Heinrich MC, von Mehren M, Patel S, McCarter MD, Owzar K, DeMatteo RP. Pathologic and Molecular Features Correlate With Long-Term Outcome After Adjuvant Therapy of Resected Primary GI Stromal Tumor: The ACOSOG Z9001 Trial. J Clin Oncol, 32(15):1563-70, 2014. Read the article.

11.        Dell DD, Held-Warmkessel J, Jakubek P, O’Mara T. Care of the open abdomen after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal surface malignancies. Oncology nursing forum, 41(4):438-41, 2014. [Comment] Read the article.

12.        Denlinger CS, Meropol NJ, Li T, Lewis NL, Engstrom PF, Weiner LM, Cheng JD, Alpaugh RK, Cooper H, Wright JJ, Cohen SJ. A Phase II Trial of the Proteasome Inhibitor Bortezomib in Patients With Advanced Biliary Tract Cancers. Clin Colorectal Canc, 13(2):81-6, 2014. Read the article.

13.        Doss M. Low dose radiation adaptive protection to control neurodegenerative diseases. Dose-response : a publication of International Hormesis Society, 12(2):277-87, 2014. Pmc4036399. Read the article.

14.        Doss M. Correcting systemic deficiencies in our scientific infrastructure. Dose-response : a publication of International Hormesis Society, 12(2):185-201, 2014. Pmc4036394. Read the article.

15.        Garcia JA, Hudes GR, Choueiri TK, Stadler WM, Wood LS, Gurtler J, Bhatia S, Joshi A, Hozak RR, Xu YH, Schwartz JD, Thompson JA. A Phase 2, Single-Arm Study of Ramucirumab in Patients With Metastatic Renal Cell Carcinoma With Disease Progression on or Intolerance to Tyrosine Kinase Inhibitor Therapy. Cancer, 120(11):1647-55, 2014. Read the article.

16.        Gowrishankar B, Ibragimova I, Zhou Y, Slifker MJ, Devarajan K, Al-Saleem T, Uzzo RG, Cairns P. MicroRNA expression signatures of stage, grade, and progression in clear cell RCC. Cancer biology & therapy, 15(3):329-41, 2014. Read the article.

17.        Gustafson HL, Yao S, Goldman BH, Lee K, Spier CM, LeBlanc ML, Rimsza LM, Cerhan JR, Habermann TM, Link BK, Maurer MJ, Slager SL, Persky DO, Miller TP, Fisher RI, Ambrosone CB, Briehl MM. Genetic polymorphisms in oxidative stress-related genes are associated with outcomes following treatment for aggressive B-cell non-Hodgkin lymphoma. Am J Hematol, 89(6):639-45, 2014. Read the article.

18.        Hakanson M, Cukierman E, Charnley M. Miniaturized pre-clinical cancer models as research and diagnostic tools. Adv Drug Deliv Rev, 69:52-66, 2014. Read the article.

19.        Hall MJ. Conflicted confidence: academic oncologists’ views on multiplex pharmacogenomic testing. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(13):1290-2, 2014. Read the article.

20.        Handorf E, Crumpler N, Gross L, Giri VN. Prevalence of the HOXB13 G84E Mutation Among Unaffected Men with a Family History of Prostate Cancer. J Genet Couns, 23(3):371-6, 2014. Read the article.

21.        Haugh KA, Shalginskikh N, Nogusa S, Skalka AM, Katz RA, Balachandran S. The interferon-inducible antiviral protein Daxx is not essential for interferon-mediated protection against avian sarcoma virus. Virology journal, 11(1):100, 2014. Pmc4049388. Read the article.

22.        Heckman CJ. Enhancing skin cancer screening through behavioral intervention. JAMA dermatology, 150(4):363-5, 2014. Pmc3984595. Read the article.

23.        Johnson ME, Robu VG, Turaka A. Nasopharyngeal Hodgkin lymphoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(11):e40-1, 2014. [Case Report]. Read the article.

24.        Johnson ME, Zhu F, Li T, Wu H, Galloway TJ, Farma JM, Perlis CS, Turaka A. Absolute lymphocyte count: a potential prognostic factor for Merkel cell carcinoma. Journal of the American Academy of Dermatology, 70(6):1028-35, 2014. Read the article.

25.        Kaiser WJ, Daley-Bauer LP, Thapa RJ, Mandal P, Berger SB, Huang CZ, Sundararajan A, Guo HY, Roback L, Speck SH, Bertin J, Gough PJ, Balachandran S, Mocarski ES. RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition. Proc Natl Acad Sci U S A, 111(21):7753-8, 2014. Read the article.

26.        Kang SW, Lang JY, Wang P, Li J, Lin MH, Chen XM, Guo M, Chen F, Chen LL, Ma CM. Optimization strategies for pulsed low-dose-rate IMRT of recurrent lung and head and neck cancers. J Appl Clin Med Phys, 15(3):102-13, 2014. Read the article.

27.        Kim SP, Gross CP, Nguyen PL, Smaldone MC, Shah ND, Karnes RJ, Thompson RH, Han LC, Yu JB, Trinh QD, Ziegenfuss JY, Sun M, Tilburt JC. Perceptions of Active Surveillance and Treatment Recommendations for Low-risk Prostate Cancer: Results from a National Survey of Radiation Oncologists and Urologists. Medical care, 52(7):579-85, 2014. Read the article.

28.        Kim SP, Gross CP, Nguyen PY, Smaldone MC, Thompson RH, Shah ND, Kutikov A, Han LC, Karnes RJ, Ziegenfuss JY, Tilburt JC. Specialty bias in treatment recommendations and quality of life among radiation oncologists and urologists for localized prostate cancer. Prostate cancer and prostatic diseases, 17(2):163-9, 2014. Read the article.

29.        Langer CJ, Novello S, Park K, Krzakowski M, Karp DD, Mok T, Benner RJ, Scranton JR, Olszanski AJ, Jassem J. Randomized, Phase III Trial of First-Line Figitumumab in Combination With Paclitaxel and Carboplatin Versus Paclitaxel and Carboplatin Alone in Patients With Advanced Non-Small-Cell Lung Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(19):2059-66, 2014. Read the article.

30.        Levy MH. Palliative care and oncology: integration leads to better care. Oncology (Williston Park, NY), 25(13):1275, 2011. Read the article.

31.        Mahadevan D, Morales C, Cooke LS, Manziello A, Mount DW, Persky DO, Fisher RI, Miller TP, Qi W. Alisertib Added to Rituximab and Vincristine Is Synthetic Lethal and Potentially Curative in Mice with Aggressive DLBCL Co-Overexpressing MYC and BCL2. PloS one, 9(6):e95184, 2014. Pmc4043492. Read the article.

32.        Manne S, Kashy D, Albrecht T, Wong YN, Flamm AL, Benson AB, Miller SM, Fleisher L, Buzaglo J, Roach N, Katz M, Ross E, Collins M, Poole D, Raivitch S, Miller DM, Kinzy TG, Liu T, Meropol NJ. Knowledge, Attitudes, and Self-efficacy as Predictors of Preparedness for Oncology Clinical Trials: A Mediational Model. Med Decis Mak, 34(4):454-63, 2014. Read the article.

33.        Marur S, Burtness B. Oropharyngeal squamous cell carcinoma treatment: current standards and future directions. Curr Opin Oncol, 26(3):252-8, 2014. Read the article.

34.        Mohler JL, Kantoff PW, Armstrong AJ, Bahnson RR, Cohen M, D’Amico AV, Eastham JA, Enke CA, Farrington TA, Higano CS, Horwitz EM, Kane CJ, Kawachi MH, Kuettel M, Kuzel TM, Lee RJ, Malcolm AW, Miller D, Plimack ER, Pow-Sang JM, Raben D, Richey S, Roach M, Rohren E, Rosenfeld S, Schaeffer E, Small EJ, Sonpavde G, Srinivas S, Stein C, Strope SA, Tward J, Shead DA, Ho M. Prostate Cancer, Version 2.2014. J Natl Compr Cancer Netw, 12(5):686-718, 2014. Read the article.

35.        Mookerjee-Basu J, Kappes DJ. New ingredients for brewing CD4(+)T (cells): TCF-1 and LEF-1. Nature immunology, 15(7):593-4, 2014. [comment]. Read the article.

36.        Pape-Zambito D, Jiang Z, Wu H, Devarajan K, Slater CM, Cai KQ, Patchefsky A, Daly MB, Chen X. Identifying a Highly-Aggressive DCIS Subgroup by Studying Intra-Individual DCIS Heterogeneity among Invasive Breast Cancer Patients. PloS one, 9(6):e100488, 2014. Pmc4076240.  Read the article.

37.        Perkins J, Boland P, Cohen SJ, Olszanski AJ, Zhou Y, Engstrom P, Astsaturov I. Successful Imatinib Therapy for Neuroendocrine Carcinoma With Activating KIT Mutation: A Case Study. Journal of the National Comprehensive Cancer Network : JNCCN, 12(6):847-52, 2014. Read the article.

38.        Prebet T, Sun ZX, Figueroa ME, Ketterling R, Melnick A, Greenberg PL, Herman J, Juckett M, Smith MR, Malick L, Paietta E, Czader M, Litzow M, Gabrilove J, Erba HP, Gore SD, Tallman MS. Prolonged Administration of Azacitidine With or Without Entinostat for Myelodysplastic Syndrome and Acute Myeloid Leukemia With Myelodysplasia-Related Changes: Results of the US Leukemia Intergroup Trial E1905. J Clin Oncol, 32(12):1242-8, 2014. Read the article.

39.        Purrington KS, Slager S, Eccles D, Yannoukakos D, Fasching PA, Miron P, Carpenter J, Chang-Claude J, Martin NG, Montgomery GW, Kristensen V, Anton-Culver H, Goodfellow P, Tapper WJ, Rafiq S, Gerty SM, Durcan L, Konstantopoulou I, Fostira F, Vratimos A, Apostolou P, Konstanta I, Kotoula V, Lakis S, Dimopoulos MA, Skarlos D, Pectasides D, Fountzilas G, Beckmann MW, Hein A, Ruebner M, Ekici AB, Hartmann A, Schulz-Wendtland R, Renner SP, Janni W, Rack B, Scholz C, Neugebauer J, Andergassen U, Lux MP, Haeberle L, Clarke C, Pathmanathan N, Rudolph A, Flesch-Janys D, Nickels S, Olson JE, Ingle JN, Olswold C, Slettedahl S, Eckel-Passow JE, Anderson SK, Visscher DW, Cafourek VL, Sicotte H, Prodduturi N, Weiderpass E, Bernstein L, Ziogas A, Ivanovich J, Giles GG, Baglietto L, Southey M, Kosma VM, Fischer HP, Reed MWR, Cross SS, Deming-Halverson S, Shrubsole M, Cai QY, Shu XO, Daly M, Weaver J, Ross E, Klemp J, Sharma P, Torres D, Rudiger T, Wolfing H, Ulmer HU, Forsti A, Khoury T, Kumar S, Pilarski R, Shapiro CL, Greco D, Heikkila P, Aittomaki K, Blomqvist C, Irwanto A, Liu JJ, Pankratz VS, Wang XS, Severi G, Mannermaa A, Easton D, Hall P, Brauch H, Cox A, Zheng W, Godwin AK, Hamann U, Ambrosone C, Toland AE, Nevanlinna H, Vachon CM, Fergus J, Network G. Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer. Carcinogenesis, 35(5):1012-9, 2014. Read the article.

40.        Sears HF. Remembrances of Hilary Koprowski from a Surgeon’s Perspective. Monoclonal antibodies in immunodiagnosis and immunotherapy, 33(3):173-6, 2014. Pmc4066234. Read the article.

41.        Shapovalov MV, Wang Q, Xu Q, Andrake M, Dunbrack RL, Jr. BioAssemblyModeler (BAM): User-Friendly Homology Modeling of Protein Homo- and Heterooligomers. PloS one, 9(6):e98309, 2014. Pmc4055448. Read the article.

42.        Simon MA, de la Riva EE, Bergan R, Norbeck C, McKoy JM, Kulesza P, Dong XQ, Schink J, Fleisher L. Improving Diversity in Cancer Research Trials: The Story of the Cancer Disparities Research Network. J Cancer Educ, 29(2):366-74, 2014. Read the article.

43.        Socol Y, Dobrzynski L, Doss M, Feinendegen LE, Janiak MK, Miller ML, Sanders CL, Scott BR, Ulsh B, Vaiserman A. Commentary: ethical issues of current health-protection policies on low-dose ionizing radiation. Dose-response : a publication of International Hormesis Society, 12(2):342-8, 2014. Pmc4036401. Read the article.

44.        Virtue SM, Manne SL, Ozga M, Kissane DW, Rubin S, Heckman C, Rosenblum N, Graff JJ. Cancer-Related Concerns Among Women With a New Diagnosis of Gynecological Cancer An Exploration of Age Group Differences. Int J Gynecol Cancer, 24(1):165-71, 2014. Read the article.

45.        von Mehren M, Randall RL, Benjamin RS, Boles S, Bui MM, Casper ES, Conrad EU, 3rd, DeLaney TF, Ganjoo KN, George S, Gonzalez RJ, Heslin MJ, Kane JM, 3rd, Mayerson J, McGarry SV, Meyer C, O’Donnell RJ, Pappo AS, Paz IB, Pfeifer JD, Riedel RF, Schuetze S, Schupak KD, Schwartz HS, Van Tine BA, Wayne JD, Bergman MA, Sundar H. Gastrointestinal stromal tumors, version 2.2014. Journal of the National Comprehensive Cancer Network : JNCCN, 12(6):853-62, 2014. Read the article.

46.        Yang B, Wei XD, Zhao YT, Ma CM. Dosimetric evaluation of integrated IMRT treatment of the chest wall and supraclavicular region for breast cancer after modified radical mastectomy. Med Dosim, 39(2):185-9, 2014. Read the article.

47.        Zhang H, Chang YC, Brennan ML, Wu JH. The structure of Rap1 in complex with RIAM reveals specificity determinants and recruitment mechanism. J Mol Cell Biol, 6(2):128-39, 2014. Read the article.

48.        Zhou Z, Sehn LH, Rademaker AW, Gordon LI, LaCasce AS, Crosby-Thompson A, Vanderplas A, Zelenetz AD, Abel GA, Rodriguez MA, Nademanee A, Kaminski MS, Czuczman MS, Millenson M, Niland J, Gascoyne RD, Connors JM, Friedberg JW, Winter JN. An enhanced International Prognostic Index (NCCN-IPI) for patients with diffuse large B-cell lymphoma treated in the rituximab era. Blood, 123(6):837-42, 2014. Read the article.

49.        Zibelman M, Xiang Q, Muchka S, Nickoloff S, Marks S. Assessing prognostic documentation and accuracy among palliative care clinicians. Journal of palliative medicine, 17(5):521-6, 2014. Read the article.


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Staff Publications Received in May 2014

 Staff Publications Received in May 2014

1.         Angevin E, Tabernero J, Elez E, Cohen SJ, Bahleda R, van Laethem JL, Ottensmeier C, Lopez-Martin JA, Clive S, Joly F, Ray-Coquard I, Dirix L, Machiels JP, Steven N, Reddy M, Hall B, Puchalski TA, Bandekar R, de Velde HV, Tromp B, Vermeulen J, Kurzrock R. A Phase I/II, Multiple-Dose, Dose-Escalation Study of Siltuximab, an Anti-Interleukin-6 Monoclonal Antibody, in Patients with Advanced Solid Tumors. Clin Cancer Res, 20(8):2192-204, 2014. Read the article.

2.         Arrangoiz R, Galloway TJ, Papavasiliou P, Ridge JA, Lango MN. Metastatic cervical carcinoma from an unknown primary: Literature review. Ear, nose, & throat journal, 93(4-5):E1-e10, 2014. Read the article.

3.         Bagshaw H, Ruth K, Horwitz EM, Chen DYT, Buyyounouski MK. Does family history of prostate cancer affect outcomes following radiotherapy? Radiother Oncol, 110(2):229-34, 2014. Read the article.

4.         Burtness B, Ilson D, Iqbal S. New directions in perioperative management of locally advanced esophagogastric cancer. American Society of Clinical Oncology educational book / ASCO American Society of Clinical Oncology Meeting, 34:e172-8, 2014. Read the article.

5.         Chang BL, Hughes L, Chen DYT, Gross L, Ruth K, Giri VN. Validation of association of genetic variants at 10q with prostate-specific antigen (PSA) levels in men at high risk for prostate cancer. BJU Int, 113(5B):E150-E6, 2014. Read the article.

6.         Chibani O, Ma C-M. HDRMC, an accelerated Monte Carlo dose calculator for high dose rate brachytherapy with CT-compatible applicators. Medical physics, 41(5):051712, 2014. Read the article.

7.         de Bono JS, Piulats JM, Pandha HS, Petrylak DP, Saad F, Aparicio LMA, Sandhu SK, Fong P, Gillessen S, Hudes GR, Wang T, Scranton J, Pollak MN. Phase II Randomized Study of Figitumumab plus Docetaxel and Docetaxel Alone with Crossover for Metastatic Castration-Resistant Prostate Cancer. Clin Cancer Res, 20(7):1925-34, 2014. Read the article.

8.         Denlinger C, Langbaum TS. Optimizing surveillance and balancing evidence with patient expectations. Journal of the National Comprehensive Cancer Network : JNCCN, 12(5 Suppl):781-4, 2014. Read the article. Read the article.

9.         Denlinger CS, Ligibel JA, Are M, Baker KS, Demark-Wahnefried W, Friedman DL, Goldman M, Jones L, King A, Ku GH, Kvale E, Langbaum TS, Leonardi-Warren K, McCabe MS, Melisko M, Montoya JG, Mooney K, Morgan MA, Moslehi JJ, O’Connor T, Overholser L, Paskett ED, Raza M, Syrjala KL, Urba SG, Wakabayashi MT, Zee P, McMillian N, Freedman-Cass D, Nccn. Survivorship: Pain Version 1.2014 Clinical Practice Guidelines in Oncology. J Natl Compr Cancer Netw, 12(4):488-500, 2014. Read the article.

10.        Feinstein E, Kaliki S, Shields CL, Ehya H, Shields JA. Choroidal metastasis from leiomyosarcoma in two cases. Oman journal of ophthalmology, 7(1):19-21, 2014. Pmc4008894. Read the article.

11.        Francescone R, Hou V, Grivennikov SI. Microbiome, inflammation, and cancer. Cancer journal (Sudbury, Mass), 20(3):181-9, 2014. Read the article.

12.        Gao WZ, Ma GX, Tan Y, Fang C, Weaver J, Jin M, Lai P, Godwin AK. Culturally Appropriate Education Intervention on Biospecimen Research Participation among Chinese Americans. Cancer Epidemiol Biomarkers Prev, 23(3):383-91, 2014. Read the article.

13.        Gradishar WJ, Anderson BO, Blair SL, Burstein HJ, Cyr A, Elias AD, Farrar WB, Forero A, Giordano SH, Goldstein LJ, Hayes DF, Hudis CA, Isakoff SJ, Ljung BME, Marcom PK, Mayer IA, McCormick B, Miller RS, Pegram M, Pierce LJ, Reed EC, Salerno KE, Schwartzberg LS, Smith ML, Soliman H, Somlo G, Ward JH, Wolff AC, Zellars R, Shead DA, Kumar R, Nccn. Breast Cancer Version 3.2014 Clinical Practice Guidelines in Oncology. J Natl Compr Cancer Netw, 12(4):542-90, 2014. Read the article.

14.        Guo F, Zhao X, Gill T, Zhou Y, Campagna M, Wang L, Liu F, Zhang P, DiPaolo L, Du Y, Xu X, Jiang D, Wei L, Cuconati A, Block TM, Guo JT, Chang J. An interferon-beta promoter reporter assay for high throughput identification of compounds against multiple RNA viruses. Antiviral research, 107c:56-65, 2014. Read the article.

15.        Ibragimova I, Dulaimi E, Slifker MJ, Chen DY, Uzzo RG, Cairns P. A global profile of gene promoter methylation in treatment-naive urothelial cancer. Epigenetics, 9(5):760-73, 2014. Read the article.

16.        Jansen K, Heirbaut L, Verkerk R, Cheng JD, Joossens J, Cos P, Maes L, Lambeir AM, De Meester I, Augustyns K, Van der Veken P. Extended Structure Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycy1-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP). J Med Chem, 57(7):3053-74, 2014. Read the article.

17.        Kelly ML, Astsaturov A, Rhodes J, Chernoff J. A Pak1/Erk Signaling Module Acts through Gata6 to Regulate Cardiovascular Development in Zebrafish. Developmental cell, 29(3):350-9, 2014. Read the article.

18.        Kim SP, Karnes RJ, Nguyen PL, Ziegenfuss JY, Thompson RH, Han LC, Shah ND, Smaldone MC, Gross CP, Frank I, Weight CJ, Beebe TJ, Tilburt JC. A national survey of radiation oncologists and urologists on recommendations of prostate-specific antigen screening for prostate cancer. BJU Int, 113(5B):E106-E11, 2014. Read the article.

19.        Koltsova EK, Grivennikov SI. IL-22 Gets to the Stem of Colorectal Cancer. Immunity, 40(5):639-41, 2014. Read the article.

20.        Lango MN, Egleston B, Fang C, Burtness B, Galloway T, Liu J, Mehra R, Ebersole B, Moran K, Ridge JA. Baseline health perceptions, dysphagia, and survival in patients with head and neck cancer. Cancer, 120(6):840-7, 2014. Pmc3951722. Read the article.

21.        Miller SM, Roussi P, Scarpato J, Wen KY, Zhu F, Roy G. Randomized trial of print messaging: the role of the partner and monitoring style in promoting provider discussions about prostate cancer screening among African American men. Psycho-Oncol, 23(4):404-11, 2014. Read the article.

22.        Pei JM, Robu V, Feder M, Cheung M, Neumann-Domer E, Talarchek J, Dulaimi E, Millenson MM, Testa JR. Copy neutral loss of heterozygosity in 20q in chronic lymphocytic leukemia/small lymphocytic lymphoma. Cancer Genet, 207(3):98-102, 2014. Read the article.

23.        Phee H, Au-Yeung BB, Pryshchep O, O’Hagan KL, Fairbairn SG, Radu M, Kosoff R, Mollenauer M, Cheng D, Chernoff J, Weiss A. Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation. eLife, 3:e02270, 2014. Pmc4017645. Read the article.

24.        Pond GR, Agarwal N, Bellmunt J, Choueiri TK, Qu A, Fougeray R, Vaughn D, James ND, Salhi Y, Albers P, Niegisch G, Galsky MD, Wong YN, Ko YJ, Stadler WM, O’Donnell PH, Sridhar SS, Vogelzang NJ, Necchi A, Di Lorenzo G, Sternberg CN, Mehta A, Sonpavde G. A nomogram including baseline prognostic factors to estimate the activity of second-line therapy for advanced urothelial carcinoma. BJU Int, 113(5B):E137-E43, 2014. Read the article.

25.        Ridge JA. Surgery in the HPV Era: The Role of Robotics and Microsurgical Techniques. American Society of Clinical Oncology educational book / ASCO American Society of Clinical Oncology Meeting, 34:154-9, 2014. Read the article.

26.        Rivers BM, Bernhardt JM, Fleisher L, Green BL. Vintafolide: a novel targeted agent for epithelial ovarian cancer. Future Oncol, 10(4):519-22, 2014. Read the article.

27.        Rybinski B, Franco-Barraza J, Cukierman E. The wound healing, chronic fibrosis, and cancer progression triad. Physiol Genomics, 46(7):223-44, 2014. Read the article.

28.        Salama JK, Golden DW, Yom SS, Garg MK, Lawson J, McDonald MW, Quon H, Ridge JA, Saba N, Smith RV, Worden F, Yeung AR, Beitler JJ. ACR Appropriateness Criteria(R) thyroid carcinoma. Oral oncology, 50(6):577-86, 2014. Read the article.

29.        Shapiro IM, Kolev VN, Vidal CM, Kadariya Y, Ring JE, Wright Q, Weaver DT, Menges C, Padval M, McClatchey AI, Xu Q, Testa JR, Pachter JA. Merlin Deficiency Predicts FAK Inhibitor Sensitivity: A Synthetic Lethal Relationship. Science translational medicine, 6(237):237ra68, 2014. Read the article.

30.        Siddiqui UD, Banerjee S, Barth B, Chauhan SS, Gottlieb KT, Konda V, Maple JT, Murad FM, Pfau PR, Pleskow DK, Tokar JL, Wang A, Rodriguez SA. Tools for endoscopic stricture dilation. Gastrointestinal endoscopy, 78(3):391-404, 2013. Read the article.

31.        Smaldone MC, Uzzo RG. Editorial comment. Urology, 83(4):779, 2014. Read the article.

32.        Sodani K, Patel A, Anreddy N, Singh S, Yang DH, Kathawala RJ, Kumar P, Talele TT, Chen ZS. Telatinib reverses chemotherapeutic multidrug resistance mediated by ABCG2 efflux transporter in vitro and in vivo. Biochemical pharmacology, 89(1):52-61, 2014. Pmc3983711. Read the article.

33.        Tomaszewski JJ, Richman EL, Sadetsky N, O’Keefe DS, Carroll PR, Davies BJ, Chan JM. Impact of Folate Intake on Prostate Cancer Recurrence Following Definitive Therapy: Data from CaPSURE (TM). J Urol, 191(4):971-6, 2014. Read the article.

34.        Vadakara J, von Mehren M. Gastrointestinal stromal tumors: management of metastatic disease and emerging therapies. Hematology/oncology clinics of North America, 27(5):905-20, 2013. Pmc3792495. Read the article.

35.        von Mehren M, Randall RL, Benjamin RS, Boles S, Bui MM, Casper ES, Conrad EU, DeLaney TF, Ganjoo KN, George S, Gonzalez RJ, Heslin MJ, Kane JM, Mayerson J, McGarry SV, Meyer C, O’Donnell RJ, Pappo AS, Paz IB, Pfeifer JD, Riedel RF, Schuetze S, Schupak KD, Schwartz HS, Van Tine BA, Wayne JD, Bergman MA, Sundar H. Soft Tissue Sarcoma, Version 2.2014 Featured Updates to the NCCN Guidelines. J Natl Compr Cancer Netw, 12(4):473-83, 2014. Read the article.

36.        Zarin P, Wong GW, Mohtashami M, Wiest DL, Zuniga-Pflucker JC. Enforcement of gamma delta-lineage commitment by the pre-T-cell receptor in precursors with weak gamma delta-TCR signals. Proc Natl Acad Sci U S A, 111(15):5658-63, 2014. Read the article.

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Staff Publications Received in April 2014

Staff Publications Received in April, 2014

1.       Adams DL, Martin SS, Alpaugh RK, Charpentier M, Tsai S, Bergan RC, Ogden IM, Catalona W, Chumsri S, Tang CM, Cristofanilli M. Circulating giant macrophages as a potential biomarker of solid tumors. Proceedings of the National Academy of Sciences of the United States of America, 111(9):3514-9, 2014.

2.       Agarwal N, Bellmunt J, Maughan BL, Boucher KM, Choueiri TK, Qu AQ, Vogelzang NJ, Fougeray R, Niegisch G, Albers P, Wong YN, Ko YJ, Sridhar SS, Tantravahi SK, Galsky MD, Petrylak DP, Vaishampayan UN, Mehta AN, Beer TM, Sternberg CN, Rosenberg JE, Sonpavde G. Six-Month Progression-Free Survival as the Primary Endpoint to Evaluate the Activity of New Agents as Second-line Therapy for Advanced Urothelial Carcinoma. Clinical Genitourinary Cancer, 12(2):130-7, 2014.

3.       Behrend SW. Patients with primary brain tumors. Oncology nursing forum, 41(3):335-6, 2014.

4.       Betancourt A, Mobley JA, Wang J, Jenkins S, Chen DQ, Kojima K, Russo J, Lamartiniere CA. Alterations in the Rat Serum Proteome Induced by Prepubertal Exposure to Bisphenol A and Genistein. Journal of Proteome Research, 13(3):1502-14, 2014.

5.       Bichakjian CK, Olencki T, Alam M, Andersen JS, Berg D, Bowen GM, Cheney RT, Daniels GA, Glass LF, Grekin RC, Grossman K, Ho AL, Lewis KD, Lydiatt DD, Morrison WH, Nehal KS, Nelson KC, Nghiem P, Perlis CS, Shaha AR, Thorstad WL, Tuli M, Urist MM, Wang TS, Werchniak AE, Wong SL, Zic JA, Hoffmann KG, McMillian NR, Ho M. Merkel Cell Carcinoma, Version 1.2014. Journal of the National Comprehensive Cancer Network, 12(3):410-24, 2014.

6.       Chen KT, Devarajan K, Milestone BN, Cooper HS, Denlinger C, Cohen SJ, Meyer JE, Hoffman JP. Neoadjuvant Chemoradiation and Duration of Chemotherapy Before Surgical Resection for Pancreatic Cancer: Does Time Interval Between Radiotherapy and Surgery Matter? Annals of Surgical Oncology, 21(2):662-9, 2014.

7.       Cook JR, Goldman B, Tubbs RR, Rimsza L, Leblanc M, Stiff P, Fisher R. Clinical Significance of MYC Expression and/or “High-grade” Morphology in Non-Burkitt, Diffuse Aggressive B-cell Lymphomas A SWOG S9704 Correlative Study. American Journal of Surgical Pathology, 38(4):494-501, 2014.

8.       Denlinger CS, Carlson RW, Are M, Baker KS, Davis E, Edge SB, Friedman DL, Goldman M, Jones L, King A, Kvale E, Langbaum TS, Ligibel JA, McCabe MS, McVary KT, Melisko M, Montoya JG, Mooney K, Morgan MA, O’Connor T, Paskett ED, Raza M, Syrjala KL, Urba SG, Wakabayashi MT, Zee P, McMillian N, Freedman-Cass D. Survivorship: Sexual Dysfunction (Male), Version 1.2013. Journal of the National Comprehensive Cancer Network, 12(3):356-63, 2014.

9.       Denlinger CS, Carlson RW, Are M, Baker KS, Davis E, Edge SB, Friedman DL, Goldman M, Jones L, King A, Kvale E, Langbaum TS, Ligibel JA, McCabe MS, McVary KT, Melisko M, Montoya JG, Mooney K, Morgan MA, O’Connor T, Paskett ED, Raza M, Syrjala KL, Urba SG, Wakabayashi MT, Zee P, McMillian N, Freedman-Cass D. Survivorship: Sexual Dysfunction (Female), Version 1.2013. Journal of the National Comprehensive Cancer Network, 12(2):184-92, 2014.

10.     Detterbeck FC, Unger M. Screening for lung cancer: moving into a new era. Annals of internal medicine, 160(5):363-4, 2014. [editorial]

11.     Garipov A, Li H, Bitler BG, Thapa RJ, Balachandran S, Zhang R. NF-YA underlies EZH2 upregulation and is essential for proliferation of human epithelial ovarian cancer cells. Molecular cancer research : MCR, 11(4):360-9, 2013. PMC3631279

12.     Hansen MR, Harris R, Barr EW, Cheng H, Girvin ME, Grubmeyer C. Backbone H-1, C-13, N-15 NMR assignments of yeast OMP synthase in unliganded form and in complex with orotidine 5′-monophosphate. Biomolecular Nmr Assignments, 8(1):103-8, 2014.

13.     Kirsanov KI, Kotova E, Makhov P, Golovine K, Lesovaya EA, Kolenko VM, Yakubovskaya MG, Tulin AV. Minor grove binding ligands disrupt PARP-1 activation pathways. Oncotarget, 5(2):428-37, 2014.

14.     Koh WJ, Greer BE, Abu-Rustum NR, Apte SM, Campos SM, Chan J, Cho KR, Cohn D, Crispens MA, DuPont N, Eifel PJ, Fader AN, Fisher CM, Gaffney DK, George S, Han E, Huh WK, Lurain JR, Martin L, Mutch D, Remmenga SW, Reynolds RK, Small W, Teng N, Tillmanns T, Valea FA, McMillian N, Hughes M. Uterine Neoplasms, Version 1.2014. Journal of the National Comprehensive Cancer Network, 12(2):248-80, 2014.

15.     Kolappaswamy K, Nazareno J, Porter WP, Klein HJ. Outbreak of pathogenic Escherichia coli in an outdoor- housed non- human primate colony. Journal of Medical Primatology, 43(2):122-4, 2014.

16.     Layfield LJ, Ehya H, Filie AC, Hruban RH, Jhala N, Joseph L, Vielh P, Pitman MB. Utilization of ancillary studies in the cytologic diagnosis of biliary and pancreatic lesions: The papanicolaou society of cytopathology guidelines for pancreatobiliary cytology. Diagnostic Cytopathology, 42(4):351-62, 2014.

17.     Lee LJ, Ratner E, Uduman M, Winter K, Boeke M, Greven KM, King S, Burke TW, Underhill K, Kim H, Boulware RJ, Yu H, Parkash V, Lu L, Gaffney D, Dicker AP, Weidhaas J. The KRAS-Variant and miRNA Expression in RTOG Endometrial Cancer Clinical Trials 9708 and 9905. PloS one, 9(4):e94167, 2014. PMC3986055

18.     Lentz CS, Halls VS, Hannam JS, Strassel S, Lawrence SH, Jaffe EK, Famulok M, Hoerauf A, Pfarr KM. wALADin Benzimidazoles Differentially Modulate the Function of Porphobilinogen Synthase Orthologs. Journal of Medicinal Chemistry, 57(6):2498-510, 2014.

19.     Mace EM, Dongre P, Hsu HT, Sinha P, James AM, Mann SS, Forbes LR, Watkin LB, Orange JS. Cell biological steps and checkpoints in accessing NK cell cytotoxicity. Immunology and Cell Biology, 92(3):245-55, 2014.

20.     Macfarlane AW 4th, Jillab M, Plimack ER, Hudes GR, Uzzo RG, Litwin S, Dulaimi E, Al-Saleem T, Campbell KS. PD-1 Expression on Peripheral Blood Cells Increases with Stage in Renal Cell Carcinoma Patients and Is Rapidly Reduced after Surgical Tumor Resection. Cancer immunology research, 2(4):320-31, 2014.

21.     Makhov P, Golovine K, Teper E, Kutikov A, Mehrazin R, Corcoran A, Tulin A, Uzzo RG, Kolenko VM. Piperlongumine promotes autophagy via inhibition of Akt/mTOR signalling and mediates cancer cell death. British journal of cancer, 110(4):899-907, 2014. PMC3929888

22.     Martin LP, Sill M, Shahin MS, Powell M, DiSilvestro P, Landrum LM, Gaillard SL, Goodheart MJ, Hoffman J, Schilder RJ. A phase II evaluation of AMG 102 (rilotumumab) in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal carcinoma: a Gynecologic Oncology Group study. Gynecologic oncology, 132(3):526-30, 2014.

23.     McLaughlin S, Mittendorf EA, Bleicher RJ, McCready DR, King TA. The 2013 Society of Surgical Oncology Susan G. Komen for the Cure Symposium: MRI in Breast Cancer: Where Are We Now? Annals of Surgical Oncology, 21(1):28-36, 2014.

24.     Menges CW, Kadariya Y, Altomare D, Talarchek J, Neumann-Domer E, Wu Y, Xiao GH, Shapiro IM, Kolev VN, Pachter JA, Klein-Szanto AJ, Testa JR. Tumor suppressor alterations cooperate to drive aggressive mesotheliomas with enriched cancer stem cells via a p53-miR-34a-c-Met axis. Cancer research, 74(4):1261-71, 2014. PMC3945416

25.     Merali S, Barrero CA, Bowler RP, Chen DE, Criner G, Braverman A, Litwin S, Yeung A, Kelsen SG. Analysis of the Plasma Proteome in COPD: Novel Low Abundance Proteins Reflect the Severity of Lung Remodeling. Copd-Journal of Chronic Obstructive Pulmonary Disease, 11(2):177-89, 2014.

26.     Motzer RJ, Jonasch E, Agarwal N, Beard C, Bhayani S, Bolger GB, Chang SS, Choueiri TK, Derweesh IH, Gupta S, Hancock SL, Kim JJ, Kuzel TM, Lam ET, Lau C, Levine EG, Lin DW, Margolin KA, Michaelson MD, Olencki T, Pili R, Plimack ER, Rampersaud EN, Redman BG, Ryan CJ, Sheinfeld J, Sircar K, Somer B, Wang J, Wilder RB, Dwyer MA, Kumar R. Kidney Cancer, Version 2.2014 Featured Updates to the NCCN Guidelines. Journal of the National Comprehensive Cancer Network, 12(2):175-82, 2014.

27.     Olszanski AJ. Current and future roles of targeted therapy and immunotherapy in advanced melanoma. Journal of managed care pharmacy : JMCP, 20(4):346-56, 2014.

28.     Osorio A, Milne RL, Kuchenbaecker K, Vaclova T, Pita G, Alonso R, Peterlongo P, Blanco I, de la Hoya M, Duran M, Diez O, Ramon YCT, Konstantopoulou I, Martinez-Bouzas C, Andres Conejero R, Soucy P, McGuffog L, Barrowdale D, Lee A, Swe B, Arver B, Rantala J, Loman N, Ehrencrona H, Olopade OI, Beattie MS, Domchek SM, Nathanson K, Rebbeck TR, Arun BK, Karlan BY, Walsh C, Lester J, John EM, Whittemore AS, Daly MB, Southey M, Hopper J, Terry MB, Buys SS, Janavicius R, Dorfling CM, van Rensburg EJ, Steele L, Neuhausen SL, Ding YC, Hansen TV, Jonson L, Ejlertsen B, Gerdes AM, Infante M, Herraez B, Moreno LT, Weitzel JN, Herzog J, Weeman K, Manoukian S, Peissel B, Zaffaroni D, Scuvera G, Bonanni B, Mariette F, Volorio S, Viel A, Varesco L, Papi L, Ottini L, Tibiletti MG, Radice P, Yannoukakos D, Garber J, Ellis S, Frost D, Platte R, Fineberg E, Evans G, Lalloo F, Izatt L, Eeles R, Adlard J, Davidson R, Cole T, Eccles D, Cook J, Hodgson S, Brewer C, Tischkowitz M, Douglas F, Porteous M, Side L, Walker L, Morrison P, Donaldson A, Kennedy J, Foo C, Godwin AK, Schmutzler RK, Wappenschmidt B, Rhiem K, Engel C, Meindl A, Ditsch N, Arnold N, Plendl HJ, Niederacher D, Sutter C, Wang-Gohrke S, Steinemann D, Preisler-Adams S, Kast K, Varon-Mateeva R, Gehrig A, Stoppa-Lyonnet D, Sinilnikova OM, Mazoyer S, Damiola F, Poppe B, Claes K, Piedmonte M, Tucker K, Backes F, Rodriguez G, Brewster W, Wakeley K, Rutherford T, Caldes T, Nevanlinna H, Aittomaki K, Rookus MA, van Os TA, van der Kolk L, de Lange JL, Meijers-Heijboer HE, van der Hout AH, van Asperen CJ, Gomez Garcia EB, Hoogerbrugge N, Collee JM, van Deurzen CH, van der Luijt RB, Devilee P, Hebon, Olah E, Lazaro C, Teule A, Menendez M, Jakubowska A, Cybulski C, Gronwald J, Lubinski J, Durda K, Jaworska-Bieniek K, Johannsson OT, Maugard C, Montagna M, Tognazzo S, Teixeira MR, Healey S, Investigators K, Olswold C, Guidugli L, Lindor N, Slager S, Szabo CI, Vijai J, Robson M, Kauff N, Zhang L, Rau-Murthy R, Fink-Retter A, Singer CF, Rappaport C, Geschwantler Kaulich D, Pfeiler G, Tea MK, Berger A, Phelan CM, Greene MH, Mai PL, Lejbkowicz F, Andrulis I, Mulligan AM, Glendon G, Toland AE, Bojesen A, Pedersen IS, Sunde L, Thomassen M, Kruse TA, Jensen UB, Friedman E, Laitman Y, Shimon SP, Simard J, Easton DF, Offit K, Couch FJ, Chenevix-Trench G, Antoniou AC, Benitez J. DNA Glycosylases Involved in Base Excision Repair May Be Associated with Cancer Risk in BRCA1 and BRCA2 Mutation Carriers. PLoS genetics, 10(4):e1004256, 2014. PMC3974638

29.     Palmer JD, Zaorsky NG, Witek M, Lu B. Molecular markers to predict clinical outcome and radiation induced toxicity in lung cancer. Journal of thoracic disease, 6(4):387-98, 2014. PMC3968560

30.     Pectasides E, Rampias T, Sasaki C, Perisanidis C, Kouloulias V, Burtness B, Zaramboukas T, Rimm D, Fountzilas G, Psyrri A. Markers of Epithelial to Mesenchymal Transition in Association with Survival in Head and Neck Squamous Cell Carcinoma (HNSCC). PloS one, 9(4):e94273, 2014. PMC3983114

31.     Pei J, Robu V, Feder M, Cheung M, Neumann-Domer E, Talarchek J, Dulaimi E, Millenson MM, Testa JR. Copy neutral loss of heterozygosity in 20q in chronic lymphocytic leukemia/small lymphocytic lymphoma. Cancer genetics, 207(3):98-102, 2014.

32.     Pisansky TM, Pugh SL, Greenberg RE, Pervez N, Reed DR, Rosenthal SA, Mowat RB, Raben A, Buyyounouski MK, Kachnic LA, Bruner DW. Tadalafil for prevention of erectile dysfunction after radiotherapy for prostate cancer: the Radiation Therapy Oncology Group [0831] randomized clinical trial. JAMA : the journal of the American Medical Association, 311(13):1300-7, 2014.

33.     Ren JH, Dai XF, Yan GL, Jin M, Liu CW, Yang KY, Wu G, Ma CMC. Acute oral mucositis in nasopharyngeal carcinoma patients treated with radiotherapy: Association with genetic polymorphism in DNA DSB repair genes. International Journal of Radiation Biology, 90(3):256-61, 2014.

34.     Russo J, Santucci-Pereira J, Russo IH. The genomic signature of breast cancer prevention. Genes, 5(1):65-83, 2014. PMC3978512

35.     Santucci-Pereira J, George C, Armiss D, Russo IH, Vanegas JE, Sheriff F, de Cicco RL, Su Y, Russo PA, Bidinotto LT, Russo J. Mimicking pregnancy as a strategy for breast cancer prevention. Breast cancer management, 2(4):283-94, 2013. PMC3984583

36.     Shaker M, Pascarelli KM, Plantinga MJ, Love MA, Lazar AJ, Ingram DR, von Mehren M, Lev D, Kipling D, Broccoli D. Differential expression of cysteine dioxygenase 1 in complex karyotype liposarcomas. Biomarkers in cancer, 6:1-10, 2014. PMC3981480

37.     Songdej N. Focal cranial hyperostosis from meningioma: a complication from previous radiation treatment for childhood T-cell acute lymphoblastic leukemia. Journal of pediatric hematology/oncology, 36(2):148-9, 2014.

38.     Swisher-McClure S, Mitra N, Woo K, Smaldone M, Uzzo R, Bekelman JE. Increasing use of dose-escalated external beam radiation therapy for men with nonmetastatic prostate cancer. International journal of radiation oncology, biology, physics, 89(1):103-12, 2014.

39.     Thomas CJ, Kotova E, Andrake M, Adolf-Bryfogle J, Glaser R, Regnard C, Tulin AV. Kinase-mediated changes in nucleosome conformation trigger chromatin decondensation via poly(ADP-ribosyl)ation. Molecular cell, 53(5):831-42, 2014. PMC3951681

40.     Tomaszewski JJ, Uzzo RG. Editorial comment. Urology, 83(5):1079-80, 2014.

41.     Wang JL, Han XM, Wong CCL, Cheng H, Aslanian A, Xu T, Leavis P, Roder H, Hedstrom L, Yates JR, Kashina A. Arginyltransferase ATE1 Catalyzes Midchain Arginylation of Proteins at Side Chain Carboxylates In Vivo. Chemistry & Biology, 21(3):331-7, 2014.

42.     Wen KY, Miller SM, Kilby L, Fleisher L, Belton TD, Roy G, Hernandez E. Preventing postpartum smoking relapse among inner city women: development of a theory-based and evidence-guided text messaging intervention. JMIR research protocols, 3(2):e20, 2014.

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Staff Publications Received in March 2014

Staff Publications Received in March 2014

1.       Bleicher RJ, Topham NS, Morrow M. Reply to letter: “Anaplastic large cell lymphomas and breast implants”. Annals of surgery, 259(1):e5, 2014. [Letter]. Read the article.

2.       Budina-Kolomets A, Balaburski GM, Bondar A, Beeharry N, Yen T, Murphy ME. Comparison of the activity of three different HSP70 inhibitors on apoptosis, cell cycle arrest, autophagy inhibition, and HSP90 inhibition. Cancer Biology & Therapy, 15(2):194-9, 2014. Read the article.

3.       Doss M. Conclusion of Increased Risk of Cataracts Associated With CT Studies of the Head May Not Be Justified. AJR American journal of roentgenology, 202(4):W413, 2014. [Letter]. Read the article.

4.       Doss M. No Increased Risk of Cancer From CT. AJR American journal of roentgenology, 202(4):W410, 2014. [Letter]. Read the article.

5.       Doss M. Radiation doses from radiological imaging do not increase the risk of cancer. The British journal of radiology, 87(1036):20140085, 2014. [Letter]. Read the article.

6.       Doss M. Adoption of linear no-threshold model violated basic scientific principles and was harmful. Archives of Toxicology, 88(3):849-52, 2014. [Letter]. Read the article.

7.       Fang CY, Egleston BL, Manzur AM, Townsend RR, Stanczyk FZ, Spiegel D, Dorgan JF. Psychological reactivity to laboratory stress is associated with hormonal responses in postmenopausal women. The Journal of international medical research, 42(2):444-56, 2014. Read the article.

8.       Gao W, Ma GX, Tan Y, Fang C, Weaver J, Jin M, Lai P, Godwin AK. Culturally Appropriate Education Intervention on Biospecimen Research Participation among Chinese Americans. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 23(3):383-91, 2014. PMC3955025. Read the article.

9.       Giersch K, Helbig M, Volz T, Allweiss L, Mancke LV, Lohse AW, Polywka S, Pollok JM, Petersen J, Taylor J, Dandri M, Lutgehetmann M. Persistent hepatitis D virus mono-infection in humanized mice is efficiently converted by hepatitis B virus to a productive co-infection. Journal of Hepatology, 60(3):538-44, 2014. Read the article.

10.     Ginzburg S, Kutikov A. Does every second really count when it comes to renal ischemia during nephron sparing surgery? Canadian Journal of Urology, 21(1):7134, 2014. [Editorial]. Read the article.

11.     Ginzburg S, Uzzo R, Al-Saleem T, Dulaimi E, Walton J, Corcoran A, Plimack E, Mehrazin R, Tomaszewski J, Viterbo R, Chen DYT, Greenberg R, Smaldone M, Kutikov A. Coexisting Hybrid Malignancy in a Solitary Sporadic Solid Benign Renal Mass: Implications for Treating Patients Following Renal Biopsy. Journal of Urology, 191(2):296-300, 2014. Read the article.

12.     Goldsack JC, Reilly C, Bush C, McElligott S, Bristol MN, Motanya UN, Field R, Vozniak JM, Wong YN, Schwartz JS, Domchek S. Impact of shortages of injectable oncology drugs on patient care. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 71(7):571-8, 2014. Read the article.

13.     Goldstein LJ, Miller BJ, Nicotera N, Pendleton D. Reducing the time from initial call to first appointment: the impact of patient access redesign and a nurse navigation program. Journal of the National Comprehensive Cancer Network : JNCCN, 12 Suppl 1:S16-8, 2014. Read the article.

14.     Gupta S, Melnyk SB, Kruger WD. Cystathionine beta-synthase-deficient mice thrive on a low-methionine diet. Faseb Journal, 28(2):781-90, 2014. Read the article.

15.     Haery L, Lugo-Pico JG, Henry RA, Andrews AJ, Gilmore TD. Histone acetyltransferase-deficient p300 mutants in diffuse large B cell lymphoma have altered transcriptional regulatory activities and are required for optimal cell growth. Molecular Cancer, 13:Article number 29, 2014. Read the article.

16.     Handorf EA, Smaldone MC. Editorial comment. Urology, 83(1):132-3; discussion 3, 2014. [Comment]. Read the article.

17.     Hardy RR, Roederer M. Leonard Herzenberg (1931-2013): The Life of FACS Obituary. Immunity, 39(6):989-91, 2013. [Obituary]. Read the article.

18.     Johnson ME, Ruth K, Buyyounouski MK, Horwitz EM. Seminal Vesicle Target Delineation for Intermediate-Risk Prostate Cancer IMRT. Practical radiation oncology, 3(2 Suppl 1):S31-2, 2013. Read the article.

19.     Johnson ME, Turaka A, Zhu F, Galloway T, Farma J, Perlis C. Absolute lymphocyte count: a novel prognostic factor for merkel cell carcinoma. Practical radiation oncology, 3(2 Suppl 1):S10-1, 2013. Read the article.

20.     Jones DZ, Ragin C, Kidd NC, Flores-Obando RE, Jackson M, McFarlane-Anderson N, Tulloch-Reid M, Kimbro KS, Kidd LR. The impact of genetic variants in inflammatory-related genes on prostate cancer risk among men of African Descent: a case control study. Hereditary Cancer in Clinical Practice, 11: Article 19, 2013. Read the article.

21.     Kocher NJ, Tomaszewski JJ, Parsons RB, Cronson BR, Altman H, Kutikov A. Splenogonadal fusion: a rare etiology of solid testicular mass. Urology, 83(1):e1-2, 2014. [Editorial]. Read the article.

22.     Law MJ, Mallory MJ, Dunbrack RL, Strich R. Acetylation of the Transcriptional Repressor Ume6p Allows Efficient Promoter Release and Timely Induction of the Meiotic Transient Transcription Program in Yeast. Molecular and Cellular Biology, 34(4):631-42, 2014. Read the article.

23.     Liang L, Zhu J, Zaorsky NG, Deng Y, Wu X, Liu Y, Liu F, Cai G, Gu W, Shen L, Zhang Z. MicroRNA-223 Enhances Radiation Sensitivity of U87MG Cells In Vitro and In Vivo by Targeting Ataxia Telangiectasia Mutated. International journal of radiation oncology, biology, physics, 88(4):955-60, 2014. Read the article.

24.     Lloyd JC, Madden-Fuentes RJ, Nelson CP, Kokorowski PJ, Wiener JS, Ross SS, Kutikov A, Routh JC. Response to “Reputation rankings for pediatric urology moderately”. Journal of Pediatric Urology, 10(1):201-2, 2014. [Letter]. Read the article.

25.     Matro JM, Goldstein LJ. How Do I Follow Patients With Early Breast Cancer After Completing Adjuvant Therapy. Current Treatment Options in Oncology, 15(1):63-78, 2014. Read the article.

26.     Meng ZJ, Ma ZY, Zhang EJ, Kosinska AD, Liu J, Zhang XY, Zhou TL, Wu J, Dahmen U, Dirsch O, Yang DL, Roggendorf M, Lu MJ. Novel Woodchuck Hepatitis Virus (WHV) Transgene Mouse Models Show Sex-Dependent WHV Replicative Activity and Development of Spontaneous Immune Responses to WHV Proteins. Journal of Virology, 88(3):1573-81, 2014. Read the article.

27.     Minton O, Berger A, Barsevick A, Cramp F, Goedendorp M, Mitchell SA, Stone PC. Cancer-Related Fatigue and Its Impact on Functioning. Cancer, 119:2124-30, 2013. Read the article.

28.     Pagoto S, Hillhouse J, Heckman CJ, Coups EJ, Stapleton J, Buller D, Turrisi R, Robinson J, Geller AC. Society of Behavioral Medicine (SBM) position statement: ban indoor tanning for minors. Translational behavioral medicine, 4(1):124-6, 2014. PMC3958596. Read the article.

29.     Price RA, Jr., Koren S, Veltchev I, Hossain M, Lin MH, Galloway T, Flanagan P, Haber J, Ma CM. Planning target volume-to-skin proximity for head-and-neck intensity modulated radiation therapy treatment planning. Practical radiation oncology, 4(1):e21-9, 2014. Read the article.

30.     Quino LAV, Chen XM, Fitzpatrick M, Shi CY, Stathakis S, Gutierrez A, Esquivel C, Mavroidis P, Alkhatib H, Papanikolaou N. Patient Specific Pre-treatment QA Verification using an EPID Approach. Technology in Cancer Research & Treatment, 13(1):1-10, 2014. Read the article.

31.     Reyngold M, Niland J, Ter Veer A, Milne D, Bekaii-Saab T, Cohen SJ, Lai L, Schrag D, Skibber JM, Small W, Jr., Weiser M, Wilkinson N, Goodman KA. Neoadjuvant Radiotherapy Use in Locally Advanced Rectal Cancer at NCCN Member Institutions. Journal of the National Comprehensive Cancer Network : JNCCN, 12(2):235-43, 2014. Read the article.

32.     Saha S, Chernoff J. Analysis of PTP1B sumoylation. Methods, 65(2):201-6, 2014. Read the article.

33.     Shaw AT, Kim DW, Mehra R, Tan DS, Felip E, Chow LQ, Camidge DR, Vansteenkiste J, Sharma S, De Pas T, Riely GJ, Solomon BJ, Wolf J, Thomas M, Schuler M, Liu G, Santoro A, Lau YY, Goldwasser M, Boral AL, Engelman JA. Ceritinib in ALK-rearranged non-small-cell lung cancer. The New England journal of medicine, 370(13):1189-97, 2014. Read the article.

34.     Shlomi T, Fan J, Tang BQ, Kruger WD, Rabinowitz JD. Quantitation of Cellular Metabolic Fluxes of Methionine. Analytical Chemistry, 86(3):1583-91, 2014. Read the article.

35.     Stiff PJ, Unger JM, Fisher RI. The Role of Myeloablation for Lymphoma Reply. New England Journal of Medicine, 370(6):575-6, 2014. [Letter]. Read the article.

36.     Su S, Scott WJ, Allen MS, Darling GE, Decker PA, McKenna RJ, Meyers BF. Patterns of survival and recurrence after surgical treatment of early stage non-small cell lung carcinoma in the ACOSOG Z0030 (ALLIANCE) trial. The Journal of thoracic and cardiovascular surgery, 147(2):747-52: Discussion 52-3, 2014. Read the article.

37.     Taguchi T, Mezaki T, Iwase F, Sekida S, Kubota S, Fukami H, Okuda K, Shinbo T, Oshima S, Iiguni Y, Testa JR, Tominaga A. Molecular Cytogenetic Analysis of the Scleractinian Coral Acropora solitaryensis Veron & Wallace 1984. Zoological Science, 31(2):89-94, 2014. Read the article.

38.     Taioli E, Joseph GR, Robertson L, Eckstein S, Ragin C. Knowledge and Prevention Practices Before Breast Cancer Diagnosis in a Cross-Sectional Study Among Survivors: Impact on Patients’ Involvement in the Decision Making Process. Journal of Cancer Education, 29(1):44-9, 2014. Read the article.

39.     Tait LM, Meyer JE, McSpadden E, Cheng JD, Baciewicz FA, Meropol NJ, Cohen SJ, Wozniak AJ, Choi M, Konski AA. Women at increased risk for cardiac toxicity following chemoradiation therapy for esophageal carcinoma. Practical radiation oncology, 3(4):e149-55, 2013. Read the article.

40.     Taylor JM. Host RNA circles and the origin of hepatitis delta virus. World journal of gastroenterology : WJG, 20(11):2971-8, 2014. PMC3961984. Read the article.

41.     Tokar JL, Walia R. Diagnostic evaluation of solid pancreatic masses. Current gastroenterology reports, 15(10):347, 2013. Read the article.

42.     Tomaszewski JJ, Uzzo RG, Kutikov A, Hrebinko K, Mehrazin R, Corcoran A, Ginzburg S, Viterbo R, Chen DY, Greenberg RE, Smaldone MC. Assessing the Burden of Complications After Surgery for Clinically Localized Kidney Cancer by Age and Comorbidity Status. Urology, 83(4):843-50, 2014. Read the article.

43.     Twelves C, Chmielowska E, Havel L, Popat S, Swieboda-Sadlej A, Sawrycki P, Bycott P, Ingrosso A, Kim S, Williams JA, Chen C, Olszanski AJ, de Besi P, Schiller JH. Randomised phase II study of axitinib or bevacizumab combined with paclitaxel/carboplatin as first-line therapy for patients with advanced non-small-cell lung cancer. Annals of Oncology, 25(1):132-8, 2014. Read the article.

44.     Wangari-Talbot J, Hopper-Borge E. Drug Resistance Mechanisms in Non-Small Cell Lung Carcinoma. Journal of cancer research updates, 2(4):265-82, 2013. PMC3952141. Read the article.

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Staff Publications Received in February 2014

Staff Publications Received in February 2014

1.         Atay S, Banskota S, Crow J, Sethi G, Rink L, Godwin AK. Oncogenic KIT-containing exosomes increase gastrointestinal stromal tumor cell invasion. Proceedings of the National Academy of Sciences of the United States of America, 111(2):711-6, 2014. Read the article.

2.         Behrend SW. Update on … tobacco control. [Column] Oncology nursing forum, 41(2):215-6, 2014. Read the article.

3.         Bepler G, Williams C, Schell MJ, Chen W, Zheng Z, Simon G, Gadgeel S, Zhao XH, Schreiber F, Brahmer J, Chiappori A, Tanvetyanon T, Pinder-Schenck M, Gray J, Haura E, Antonia S, Fischer JR. Randomized International Phase III Trial of ERCC1 and RRM1 Expression-Based Chemotherapy Versus Gemcitabine/Carboplatin in Advanced Non-Small-Cell Lung Cancer. Journal of Clinical Oncology, 31(19):2404-12, 2013. Read the article.

4.         Bleicher RJ. Breast magnetic resonance imaging as it is, in contrast to how we wish it to be. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(5):370-2, 2014. Read the article.

5.         Choi W, Porten S, Kim S, Willis D, Plimack ER, Hoffman-Censits J, Roth B, Cheng T, Tran M, Lee IL, Melquist J, Bondaruk J, Majewski T, Zhang S, Pretzsch S, Baggerly K, Siefker-Radtke A, Czerniak B, Dinney CP, McConkey DJ. Identification of distinct Basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy. Cancer cell, 25(2):152-65, 2014. Read the article.

6.         Chou W-yS, Prestin A, Lyons C, Wen K-y. Web 2.0 for health promotion: Reviewing the current evidence. American Journal of Public Health, 103 (1):e9-e18, 2013. Read the article.

7.         Coccia PF, Pappo AS, Altman J, Bhatia S, Borinstein SC, Flynn J, Frazier AL, George S, Goldsby R, Hayashi R, Huang MS, Johnson RH, Beaupin LK, Link MP, Oeffinger KC, Orr KM, Reed D, Spraker HL, Thomas DA, von Mehren M, Wechsler DS, Whelan KF, Zebrack B, Shead DA, Sundar H. Adolescent and Young Adult Oncology, Version 2.2014. Journal of the National Comprehensive Cancer Network, 12(1):21-32, 2014. Read the article.

8.         Coffey F, Lee SY, Buus TB, Lauritsen JP, Wong GW, Joachims ML, Thompson LF, Zuniga-Pflucker JC, Kappes DJ, Wiest DL. The TCR ligand-inducible expression of CD73 marks gammadelta lineage commitment and a metastable intermediate in effector specification. The Journal of experimental medicine, 211(2):329-43, 2014. PMC3920555. Read the article.

9.         DeMatteo RP, Ballman KV, Antonescu CR, Corless C, Kolesnikova V, von Mehren M, McCarter MD, Norton J, Maki RG, Pisters PWT, Demetri GD, Brennan MF, Owzar K, Acosog. Long-term Results of Adjuvant Imatinib Mesylate in Localized, High-Risk, Primary Gastrointestinal Stromal Tumor ACOSOG Z9000 (Alliance) Intergroup Phase 2 Trial. Annals of Surgery, 258(3):422-9, 2013. Read the article.

10.        Denlinger CS, Carlson RW, Are M, Baker KS, Davis E, Edge SB, Friedman DL, Goldman M, Jones L, King A, Kvale E, Langbaum TS, Ligibel JA, McCabe MS, McVary KT, Melisko M, Montoya JG, Mooney K, Morgan MA, O’Connor T, Paskett ED, Raza M, Syrjala KL, Urba SG, Wakabayashi MT, Zee P, McMillian N, Freedman-Cass D. Survivorship: Introduction and Definition. Journal of the National Comprehensive Cancer Network, 12(1):34-45, 2014. Read the article.

11.        Dong B, Duan X, Chow HY, Chen L, Lu H, Wu W, Hauck B, Wright F, Kapranov P, Xiao W. Proteomics Analysis of Co-Purifying Cellular Proteins Associated with rAAV Vectors. PloS one, 9(2):e86453, 2014. PMC3911921. Read the article.

12.        Doss M. Adoption of linear no-threshold model violated basic scientific principles and was harmful : Letter from Mohan Doss regarding Edward Calabrese’s paper “How the US National Academy of Sciences misled the world community on cancer risk assessment: new findings challenge historical foundations of the linear dose response” (Arch Toxicol (2013) 87:2063-2081) and the Letter from Ralph J Cicerone (Arch Toxicol (2014) 88:171-172) [Letter]. Archives of toxicology, 88(3):849-52, 2014. Read the article.

13.        Duncan KE, Cook PM, Gavett SH, Dailey LA, Mahoney RK, Ghio AJ, Roggli VL, Devlin RB. In vitro determinants of asbestos fiber toxicity: effect on the relative toxicity of Libby amphibole in primary human airway epithelial cells. Particle and Fibre Toxicology, 11:article 2, 2014. Read the article.

14.        Eldib A, Jin L, Li J, Charlie Ma CM. Investigation of the clinical potential of scattering foil free electron beams. Physics in medicine and biology, 59(4):819-36, 2014. Read the article.

15.        Evans AA, London WT, Gish RG, Cohen C, Block TM. Chronic HBV infection outside treatment guidelines: is treatment needed? Antiviral Therapy, 18(2):229-35, 2013. Read the article.

16.        Falk RT, Brinton LA, Dorgan JF, Fuhrman BJ, Veenstra TD, Xu X, Gierach GL. Relationship of serum estrogens and estrogen metabolites to postmenopausal breast cancer risk: a nested case-control study. Breast Cancer Research, 15(2):R34, 2013. Read the article.

17.        Fazelinia H, Xu M, Cheng H, Roder H. Ultrafast Hydrogen Exchange Reveals Specific Structural Events during the Initial Stages of Folding of Cytochrome c. Journal of the American Chemical Society, 136(2):733-40, 2014. Read the article.

18.        Ferris JS, Daly MB, Buys SS, Genkinger JM, Liao Y, Terry MB. Oral contraceptive and reproductive risk factors for ovarian cancer within sisters in the breast cancer family registry. British journal of cancer, 110(4):1074-80, 2014. PMC3929882. Read the article.

19.        Gabriel KP, Klifa C, Perez A, Kriska AM, High RR, Snetselaar L, Dorgan JF. Adolescent and Young Adult Exposure to Physical Activity and Breast Density. Medicine and Science in Sports and Exercise, 45(8):1515-23, 2013. Read the article.

20.        Handorf EA, Bekelman JE, Heitjan DF, Mitra N. EVALUATING COSTS WITH UNMEASURED CONFOUNDING: A SENSITIVITY ANALYSIS FOR THE TREATMENT EFFECT. Annals of Applied Statistics, 7(4):2062-80, 2013. Read the article.

21.        Hodak E, Lessin S, Friedland R, Freud T, David M, Pavlovsky L, Shapiro J, Cohen AD. New Insights into Associated Co-morbidities in Patients with Cutaneous T-cell Lymphoma (Mycosis Fungoides). Acta Dermato-Venereologica, 93(4):451-5, 2013. Read the article.

22.        Hurria A, Wildes T, Blair SL, Browner IS, Cohen HJ, deShazo M, Dotan E, Edil BH, Extermann M, Ganti AKP, Holmes HM, Jagsi R, Karlekar MB, Keating NL, Korc-Grodzicki B, McKoy JM, Medeiros BC, Mrozek E, O’Connor T, Rugo HS, Rupper RW, Silliman RA, Stirewalt DL, Tew WP, Walter LC, Weir AB, Bergman MA, Sundar H. Senior Adult Oncology, Version 2.2014. Journal of the National Comprehensive Cancer Network, 12(1):82-126, 2014. Read the article.

23.        Janne PA, Cohen RB, Laird AD, Mace S, Engelman JA, Ruiz-Soto R, Rockich K, Xu J, Shapiro GI, Martinez P, Felip E. Phase I Safety and Pharmacokinetic Study of the PI3K/mTOR Inhibitor SAR245409 (XL765) in Combination with Erlotinib in Patients with Advanced Solid Tumors. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 9(3):316-23, 2014. Read the article.

24.        Kaveh R, Li YS, Ranjbar S, Tehrani R, Brueck CL, Van Aken B. Changes in Arabidopsis thaliana Gene Expression in Response to Silver Nanoparticles and Silver Ions. Environmental Science & Technology, 47(18):10637-44, 2013. Read the article.

25.        Lal S, Burkhart RA, Beeharry N, Bhattacharjee V, Londin ER, Cozzitorto JA, Romeo C, Jimbo M, Norris ZA, Yeo CJ, Sawicki JA, Winter JM, Rigoutsos I, Yen TJ, Brody JR. HuR Posttranscriptionally Regulates WEE1: Implications for the DNA Damage Response in Pancreatic Cancer Cells. Cancer research, 74(4):1128-40, 2014. Read the article.

26.        Licciulli S, Maksimoska J, Zhou C, Troutman S, Kota S, Liu Q, Duron S, Campbell D, Chernoff J, Field J, Marmorstein R, Kissil JL. FRAX597, a Small Molecule Inhibitor of the p21-activated Kinases, Inhibits Tumorigenesis of Neurofibromatosis Type 2 (NF2)-associated Schwannomas. Journal of Biological Chemistry, 288(40):29105-14, 2013. Read the article.

27.        Little JL, Serzhanova V, Izumchenko E, Egleston BL, Parise E, Klein-Szanto AJ, Loudon G, Shubina M, Seo S, Kurokawa M, Ochs MF, Golemis EA. A requirement for Nedd9 in luminal progenitor cells prior to mammary tumorigenesis in MMTV-HER2/ErbB2 mice. Oncogene, 33(4):411-20, 2014. Read the article.

28.        Montalvo GL, Gai F, Roder H, DeGrado WF. Slow Folding-Unfolding Kinetics of an Octameric beta-Peptide Bundle. Acs Chemical Biology, 9(1):276-81, 2014. Read the article.

29.        Moy B, Bradbury AR, Helft PR, Egleston BL, Sheikh-Salah M, Peppercorn J. Correlation Between Financial Relationships With Commercial Interests and Research Prominence at an Oncology Meeting. Journal of Clinical Oncology, 31(21):2678-84, 2013. Read the article.

30.        Tulina NM, Chen WF, Chen JH, Sowcik M, Sehgal A. Day-night cycles and the sleep-promoting factor, Sleepless, affect stem cell activity in the Drosophila testis. Proceedings of the National Academy of Sciences of the United States of America, 111(8):3026-31, 2014. Read the article.

31.        Wang X, Wang Y, Zhou Y, Hendron E, Mancarella S, Andrake MD, Rothberg BS, Soboloff J, Gill DL. Distinct Orai-coupling domains in STIM1 and STIM2 define the Orai-activating site. Nature communications, 5:3183, 2014. Read the article.

32.        Zaorsky NG, Yamoah K, Thakur ML, Trabulsi EJ, Showalter TN, Hurwitz MD, Dicker AP, Den RB. A paradigm shift from anatomic to functional and molecular imaging in the detection of recurrent prostate cancer. Future oncology (London, England), 10(3):457-74, 2014. Read the article.

33.        Zhang WZ, Grivennikov SI. Top Notch cancer stem cells by paracrine NF-kappa B signaling in breast cancer. Breast Cancer Research, 15(5):316, 2013. Read the article.

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Staff Publications Received in January 2014

Staff Publications Received in January 2014

1.            Ahmed AA, Egleston B, Holliday E, Eastwick G, Takita C, Jagsi R. Gender Trends in Radiation Oncology in the United States: A 30-Year Analysis. International Journal of Radiation Oncology Biology Physics, 88(1):33-8, 2014. Read the article.

2.            Burt RW, Cannon JA, David DS, Early DS, Ford JM, Giardiello FM, Halverson AL, Hamilton SR, Hampel H, Ismail MK, Jasperson K, Klapman JB, Lazenby AJ, Lynch PM, Mayer RJ, Ness RM, Provenzale D, Rao MS, Shike M, Steinbach G, Terdiman JP, Weinberg D, Dwyer M, Freedman-Cass D. Colorectal Cancer Screening Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network, 11(12):1538-75, 2013.  Read the article.

3.            Chen C, Ha BH, Thevenin AF, Lou HJ, Zhang R, Yip KY, Peterson JR, Gerstein M, Kim PM, Filippakopoulos P, Knapp S, Boggon TJ, Turk BE. Identification of a Major Determinant for Serine-Threonine Kinase Phosphoacceptor Specificity. Molecular Cell, 53(1):140-7, 2014.  Read the article.

4.            Daly JM. A marriage of databases produces knowledge offspring. [comment] Annals of surgery, 258(6):845-6, 2013.  Read the article.

5.            Dames DN, Blackman E, Butler R, Taioli E, Eckstein S, Devarajan K, Griffith-Bowe A, Gomez P, Ragin C. High-Risk Cervical Human Papillomavirus Infections among Human Immunodeficiency Virus-Positive Women in the Bahamas. PloS one, 9(1):e85429, 2014. PMC3900425.  Read the article.

6.            Desilets DJ, Banerjee S, Barth BA, Bhat YM, Gottlieb KT, Maple JT, Pfau PR, Pleskow DK, Siddiqui UD, Tokar JL, Wang A, Rodriguez SA. New devices and techniques for management of pancreatic fluid collections. Gastrointestinal endoscopy, 77(6):835-8, 2013.  Read the article.

7.            Gabitova L, Gorin A, Astsaturov I. Molecular Pathways: Sterols and Receptor Signaling in Cancer. Clinical Cancer Research, 20(1):28-34, 2014.  Read the article.

8.            Ginzburg S, Golovine KV, Makhov PB, Uzzo RG, Kutikov A, Kolenko VM. Piperlongumine Inhibits NF-kappa B Activity and Attenuates Aggressive Growth Characteristics of Prostate Cancer Cells. Prostate, 74(2):177-86, 2014.  Read the article.

9.            Han LC, Kim SP, Gross CP, Ross JS, Van Houten HK, Smaldone MC, Krambeck AE, Shah ND. Association of physician specialty and medical therapy for benign prostatic hyperplasia. Medical care, 52(2):128-36, 2014.  Read the article.

10.          Harmon CS, DePrimo SE, Figlin RA, Hudes GR, Hutson TE, Michaelson MD, Negrier S, Kim ST, Huang X, Williams JA, Eisen T, Motzer RJ. Circulating proteins as potential biomarkers of sunitinib and interferon-alpha efficacy in treatment-naive patients with metastatic renal cell carcinoma. Cancer Chemotherapy and Pharmacology, 73(1):151-61, 2014.  Read the article.

11.          Heckman KL, DeCoteau W, Estevez A, Reed KJ, Costanzo W, Sanford D, Leiter JC, Clauss J, Knapp K, Gomez C, Mullen P, Rathbun E, Prime K, Marini J, Patchefsky J, Patchefsky AS, Hailstone RK, Erlichman JS. Custom Cerium Oxide Nanoparticles Protect against a Free Radical Mediated Autoimmune Degenerative Disease in the Brain. Acs Nano, 7(12):10582-96, 2013.  Read the article.

12.          Held-Warmkessel J, Schiech L. Non-small cell lung cancer: Recent advances. Nursing, 44(2):32-42, 2014.  Read the article.

13.          Isayeva T, Xu J, Dai Q, Whitley AC, Bonner J, Nabell L, Spencer S, Carroll W, Jones G, Ragin C, Brandwein-Gensler M. African Americans with oropharyngeal carcinoma have significantly poorer outcomes despite similar rates of human papillomavirus-mediated carcinogenesis. Human pathology, 45(2):310-9, 2014.  Read the article.

14.          Jin L, Eldib A, Li J, Emam I, Fan J, Wang L, Ma CM. Measurement and Monte Carlo simulation for energy- and intensity-modulated electron radiotherapy delivered by a computer-controlled electron multileaf collimator. Journal of applied clinical medical physics / American College of Medical Physics, 15(1):4506, 2014.  Read the article.

15.          Kerlin MP, Tokar JL. Acute gastrointestinal bleeding. [comment].Annals of internal medicine, 159(11):793-4, 2013.  Read the article.

16.          Lillington L, Scaramuzzo L, Friese C, Sein E, Harrison K, LeFebvre KB, Fessele K. Improving Practice One Patient, One Nurse, One Day at a Time: Design and Evaluation of a Quality Education Workshop for Oncology Nurses. Clinical Journal of Oncology Nursing, 17(6):584-7, 2013.  Read the article.

17.          Loveland-Jones CE, Ruth K, Sigurdson ER, Egleston BL, Boraas M, Bleicher RJ. Patterns of nodal staging during breast conservation surgery in the medicare patient: will the ACOSOG Z0011 trial change the pattern of care? Breast cancer research and treatment, 143(3):571-7, 2014.  Read the article.

18.          Manne S, Myers S, Ozga M, Kissane D, Kashy D, Rubin S, Heckman C, Rosenblum N. Holding back sharing concerns, dispositional emotional expressivity, perceived unsupportive responses and distress among women newly diagnosed with gynecological cancers. General Hospital Psychiatry, 36(1):81-7, 2014.  Read the article.

19.          Mentlik- James A, Cohen AD, Campbell KS. Combination Immune Therapies to Enhance Anti-Tumor Responses by NK Cells. Frontiers in immunology, 4:481, 2013. PMC3870292.  Read the article.

20.          Mohler JL, Kantoff PW, Armstrong AJ, Bahnson RR, Cohen M, D’Amico AV, Eastham JA, Enke CA, Farrington TA, Higano CS, Horwitz EM, Kawachi MH, Kuettel M, Lee RJ, MacVicar GR, Malcolm AW, Miller D, Plimack ER, Pow-Sang JM, Richey S, Roach M, Rohren E, Rosenfeld S, Small EJ, Srinivas S, Stein C, Strope SA, Tward J, Walsh PC, Shead DA, Ho M. Prostate Cancer, Version 1.2014 Featured Updates to the NCCN Guidelines. Journal of the National Comprehensive Cancer Network, 11(12):1471-9, 2013.  Read the article.

21.          Moore R, Cai KQ, Tao W, Smith ER, Xu XX. Differential requirement for Dab2 in the development of embryonic and extra-embryonic tissues. BMC Dev Biol, 13:39, 2013.  Read the article.

22.          Natsuizaka M, Kinugasa H, Kagawa S, Whelan KA, Naganuma S, Subramanian H, Chang S, Nakagawa KJ, Rustgi NL, Kita Y, Natsugoe S, Basu D, Gimotty PA, Klein-Szanto AJ, Diehl JA, Nakagawa H. IGFBP3 promotes esophageal cancer growth by suppressing oxidative stress in hypoxic tumor microenvironment. American journal of cancer research, 4(1):29-41, 2014. PMC3902230.  Read the article.

23.          Naumann RW, Coleman RL, Burger RA, Sausville EA, Kutarska E, Ghamande SA, Gabrail NY, DePasquale SE, Nowara E, Gilbert L, Gersh RH, Teneriello MG, Harb WA, Konstantinopoulos PA, Penson RT, Symanowski JT, Lovejoy CD, Leaman CP, Morgenstern DE, Messmann RA. PRECEDENT: A Randomized Phase II Trial Comparing Vintafolide (EC145) and Pegylated Liposomal Doxorubicin (PLD) in Combination Versus PLD Alone in Patients With Platinum-Resistant Ovarian Cancer. Journal of Clinical Oncology, 31(35):4400-+, 2013.  Read the article.

24.          Paltser G, Liu XJ, Yantha J, Winer S, Tsui H, Wu P, Maezawa Y, Cahill LS, Laliberte CL, Ramagopalan SV, DeLuca GC, Sadovnick AD, Astsaturov I, Ebers GC, Henkelman RM, Salter MW, Dosch HM. TRPV1 Gates Tissue Access and Sustains Pathogenicity in Autoimmune Encephalitis. Molecular Medicine, 19:149-59, 2013.  Read the article.

25.          Patrick-Miller L, Egleston BL, Daly M, Stevens E, Fetzer D, Forman A, Bealin L, Rybak C, Peterson C, Corbman M, Bradbury AR. Implementation and outcomes of telephone disclosure of clinical BRCA1/2 test results. Patient Education and Counseling, 93(3):413-9, 2013.  Read the article.

26.          Perini GF, Pro B. Brentuximab Vedotin in CD30+ Lymphomas. Biologics in therapy, 3:15-23, 2013. PMC3873074.  Read the article.

27.          Poleshko A, Mansfield KM, Burlingame CC, Andrake MD, Shah NR, Katz RA. The human protein PRR14 tethers heterochromatin to the nuclear lamina during interphase and mitotic exit. Cell reports, 5(2):292-301, 2013. PMC3867587.  Read the article.

28.          Ridge JA, Lawson J, Yom SS, Garg MK, McDonald MW, Quon H, Saba N, Salama JK, Smith RV, Worden F, Yeung AR, Beitler JJ. American College of Radiology Appropriateness Criteria (R) treatment of stage I T1 glottic cancer. Head and Neck-Journal for the Sciences and Specialties of the Head and Neck, 36(1):3-8, 2014.  Read the article.

29.          Shen C, Chien CR, Geynisman DM, Smieliauskas F, Shih YC. A review of economic impact of targeted oral anticancer medications. Expert review of pharmacoeconomics & outcomes research, 14(1):45-69, 2014.  Read the article.

30.          Thomay AA, Nagorney DM, Cohen SJ, Sigurdson ER, Truty MJ, Burtness B, Hall MJ, Chun YS. Modern Chemotherapy Mitigates Adverse Prognostic Effect of Regional Nodal Metastases in Stage IV Colorectal Cancer. Journal of Gastrointestinal Surgery, 18(1):69-73, 2014.  Read the article.

31.          Tseng M, Byrne C, Kurzer MS, Fang CY. Equol-Producing Status, Isoflavone Intake, and Breast Density in a Sample of U.S. Chinese Women. Cancer Epidemiology Biomarkers & Prevention, 22(11):1975-83, 2013.  Read the article.

32.          Van Cleave JH, Egleston BL, Ercolano E, McCorkle R. Symptom Distress in Older Adults Following Cancer Surgery. Cancer Nursing, 36(4):292-300, 2013.  Read the article.

33.          Wang MJ, Mehta A, Block TM, Marrero J, Di Bisceglie AM, Devarajan K. A comparison of statistical methods for the detection of hepatocellular carcinoma based on serum biomarkers and clinical variables. Bmc Medical Genomics, 6:S9, 2013.  Read the article.

34.          Wu TL, Li H, Faust SM, Chi E, Zhou SZ, Wright F, High KA, Ertl HCJ. CD8(+) T Cell Recognition of Epitopes Within the Capsid of Adeno-associated Virus 8-based Gene Transfer Vectors Depends on Vectors’ Genome. Molecular Therapy, 22(1):42-51, 2014.  Read the article.

Competitive Grant Awards, Notifications Received December 1, 2013 through December 31, 2014

PI: Egleston, Brian               Agency:   NIH, prime: Univ.   Title:  Pilot Study of Metabolomic Profiles and Epithelial Ovarian

R01 Supplement                     of MD, Baltimore               Cancer Risk

This administrative supplement is a subcontract to the University of Maryland, Baltimore.

PI: Egleston, Brian               Agency:   NIH, prime: Univ.   Title:  Adolescent Sex Hormones and Breast Density in Young

R03                                             of MD, Baltimore               Women

This project is a subcontract to University of Maryland, Baltimore.

PI: Sigal, Luis J                     Agency:   NIH, prime: GA       Title:  Immune Mechanisms that Control Ectromelia Virus Infection

U01                                             Regents Univ.                    Discretionary Funds

This award provides IMVC Discretionary Funds to be used for the purchase of a Leica CM3050 S Research Cryostat.

PI: Sykes, Stephen M          Agency:   WW SMITH              Title:  Control of Redox Homeostasis by JNK Signaling in Acute

Lyeloid Leukemis: Mechanisms and Therapeutic Implications

The major goals of this project are:  1) To define the molecular pathways utilized by the JNK/JUN axis to resist conventional

anti‑AML chemotherapies; and 2) To exploit the JNK/JUN signaling pathway to augment AML therapy.

PI: Testa, Joseph R             Agency:   NIH                            Title:  Pathogenesis of Malignant Mesothelioma by the Human

R01                                                                                            Polycomb Complex BAP1‑ASXL

The major goals of this project are: 1) To use a direct in vivo genetic approach to determine if heterozygous Bap1 (+/mut) mice are

predisposed to the development of various spontaneous tumors, including MM, and to accelerated asbestos‑induced MM; 2) To

use conditional knockout mice to determine if somatic loss of Bap1 alone in the mesothelium is capable of driving mesothelial

hyperplasia and/or frank MM, and if somatic Bap1 inactivation combined with loss of Nf2 and Cdkn2a results in more rapid

development and/or more aggressive disease, with potential prognostic and novel therapeutic implications; 3) To define the

spectrum of BAP1 and ASXL1/2 mutations in human MM specimens/cell lines and determine how these mutations affect binding

and function of BAP1 in complex with ASXL1/2 and other PR‑DUB complex proteins, and define the transcriptome and cellular

phenotype which are altered as a consequence of mutation of BAP1 and other PR‑DUB components in MM cells; and 4) To

determine the composition of the native PR‑DUB macromolecular protein complexes that contain wild‑type BAP1 and ASXL1/2 in

mesothelial cells and in BAP1‑ and/or ASXL1/2‑deficient MM cells to compare normal‑ and tumor‑specific subunit structure and the

role of these complexes in epigenetic dysregulation that occurs in MM.

PI: Yang, Zeng‑jie                 Agency:   NIH                            Title:  Leukotriene‑Induced Nestin Expression Promotes

R01                                                                                            Medulloblastoma Tumorigenesis

The major goals of this project are: 1) To determine the molecular basis for Nestin induction in Ptc‑deficient GNPs and tumor cells 2) To determine how Nestin regulates Shh signaling; and 3) To determine the role of Nestin in MB initiation and progression.

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